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妊娠期高反应性疟疾性脾肿大

Hyperreactive malarial splenomegaly in pregnancy.

作者信息

Bates I

机构信息

Komfo Anokye Teaching Hospital, Kumasi, Ghana.

出版信息

Trop Doct. 1991 Jul;21(3):101-3. doi: 10.1177/004947559102100304.

DOI:10.1177/004947559102100304
PMID:1926546
Abstract

Hyperreactive malarial splenomegaly (HMS) is common in many tropical areas and particularly affects women of reproductive age. It is associated with anaemia which can be debilitating in patients already compromised by anaemia due to poor nutrition and pregnancy. The course of the disorder in pregnancy is commonly punctuated by episodes of haemolytic anaemia which can be life-threatening to the mother and cause increased fetal morbidity and loss. Management of the chronic state consists of lifelong anti-malarial therapy supplemented by haematinics. Blood transfusions may be required to treat episodes of severe haemolysis.

摘要

高反应性疟疾脾肿大(HMS)在许多热带地区很常见,尤其影响育龄妇女。它与贫血有关,对于那些因营养不良和怀孕而本已贫血的患者来说,贫血会使其身体衰弱。孕期该疾病的病程通常以溶血性贫血发作为特征,这对母亲可能会危及生命,并导致胎儿发病率增加和流产。慢性病态的管理包括终身抗疟疾治疗,并辅以补血药。可能需要输血来治疗严重溶血发作。

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Treatment of suspected hyper-reactive malarial splenomegaly (HMS) in pregnancy with mefloquine.
妊娠疑似高反应性疟脾肿大(HMS)的甲氟喹治疗。
Am J Trop Med Hyg. 2014 Apr;90(4):609-611. doi: 10.4269/ajtmh.13-0706. Epub 2014 Mar 3.