Egwunyenga O A, Ajayi J A, Duhlinska-Popova D D
Zoology Department, Delta State University, Abraka, Nigeria.
Indian J Malariol. 1997 Mar;34(1):17-24.
The effect of malaria parasitaemia on spleen size and anaemia in 1,905 pregnant women in Jos Plateau highlands, Bauchi Savannah plains and Ethiope river basin of Nigeria was evaluated. The overall spleen rates in Jos Plateau, Bauchi and Ethiope were 15, 23, 16.33 and 10.71% respectively. Higher cases of palpable spleen were detected in pregnant women than non-pregnant controls. Spleen rates also showed seasonal variation, but not very significant. Malaria prevalence rates were higher than spleen rates. In all three study sites, parasitaemic pregnant women had significantly lower haemoglobin values than malaria negative mothers, especially among primigravids. However, there was no constant association between higher parasite density and splenomegaly, since few cases of enlarged spleens were also recorded among subjects with low parasitaemia. Severe anaemia was predominant among parasitaemic pregnant women with high spleen classes.
对尼日利亚乔斯高原高地、包奇萨凡纳平原和埃塞俄比亚河流域的1905名孕妇，评估了疟疾寄生虫血症对脾脏大小和贫血的影响。乔斯高原、包奇和埃塞俄比亚的总体脾脏率分别为15%、23%、16.33%和10.71%。与未怀孕的对照组相比，孕妇中可触及脾脏的病例更多。脾脏率也呈现季节性变化，但不太显著。疟疾患病率高于脾脏率。在所有三个研究地点，患有寄生虫血症的孕妇血红蛋白值显著低于疟疾阴性的母亲，尤其是初产妇。然而，较高的寄生虫密度与脾肿大之间没有恒定的关联，因为在寄生虫血症低的受试者中也记录到少数脾脏肿大的病例。严重贫血在脾脏等级高的患有寄生虫血症的孕妇中占主导地位。
