Kim Dohee, Cho Hyun-Chul, Park Jin-Wan, Lee Won-Ae, Kim You-Me, Chung Phil-Sang, Park Seok-Gun, Ahn Woong-Sik, Han Sei-Jun, Park Choong-Hak
Division of Endocrinology and Metabolism, Department of Internal Medicine, Dankook University, College of Medicine, Cheonan, Republic of Korea.
Thyroid. 2009 Mar;19(3):305-8. doi: 10.1089/thy.2008.0307.
Struma ovarii is a highly specialized form of mature ovarian teratoma consisting of thyroid tissue and exhibiting all the histological features of the thyroid gland. Malignant transformation of thyroid tissue in struma ovarii and metastasis are extremely uncommon. In rare cases, benign thyroid tissue may spread to the peritoneal cavity, and pathologic examination of the peritoneal implants shows multiple nodules of varying sizes of mature thyroid tissue similar to struma ovarii. This condition is termed "peritoneal strumosis."
We report a 49-year-old woman with struma ovarii complicated by peritoneal strumosis with thyrotoxicosis. After surgical resection of the struma ovarii and peritoneal strumosis the patient became euthyroid.
To the best of our knowledge this is the first report of a patient with peritoneal strumosis complicated by thyrotoxicosis. The relative contribution to circulating thyroid hormones by the patient's struma ovarii as compared to the peritoneal strumosis is not known.
卵巢甲状腺肿是成熟卵巢畸胎瘤的一种高度特化形式，由甲状腺组织构成，并具有甲状腺的所有组织学特征。卵巢甲状腺肿中甲状腺组织的恶性转化和转移极为罕见。在罕见情况下，良性甲状腺组织可能扩散至腹腔，腹腔种植灶的病理检查显示有多个大小不一的成熟甲状腺组织结节，类似于卵巢甲状腺肿。这种情况被称为“腹腔甲状腺肿病”。
我们报告了一名49岁患有卵巢甲状腺肿并伴有腹腔甲状腺肿病及甲状腺毒症的女性。在手术切除卵巢甲状腺肿和腹腔甲状腺肿病后，患者甲状腺功能恢复正常。
据我们所知，这是首例伴有甲状腺毒症的腹腔甲状腺肿病患者的报告。与腹腔甲状腺肿病相比，患者卵巢甲状腺肿对循环甲状腺激素的相对贡献尚不清楚。
