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妊娠卵巢甲状腺肿和腹腔甲状腺肿。

Struma ovarii and peritoneal strumosis during pregnancy.

机构信息

Department of Obstetrics and Gynecology, Peking University First Hospital, 100034, Beijing, P.R. China.

出版信息

BMC Pregnancy Childbirth. 2021 May 2;21(1):347. doi: 10.1186/s12884-021-03815-4.

DOI:10.1186/s12884-021-03815-4
PMID:33934699
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8091791/
Abstract

BACKGROUND

Struma ovarii is a special type of ovarian dermoid cyst and accounts for approximately 2-3 % of all dermoid tumours. Benign struma ovarii may manifest as distant metastasis, called peritoneal strumosis, which makes it biologically similar to malignancy, and has been reported in limited cases but never discovered during pregnancy.

CASE PRESENTATION

We report a patient with a history of right struma ovarii cystectomy. During pregnancy, pelvic masses with non-specific clinical presentation were found again. During the caesarean section, contralateral struma ovarii with dissemination of nodules in the peritoneal cavity was found, and pathology revealed that the masses were thyroid follicle ovarian goitres. DISCUSSION AND CONCLUSIONS: Recurrent benign struma ovarii with extraovarian dissemination is a rare aggressive clinical manifestation different from malignancy. It is emphasized that adequate assessment and complete resection of suspicious masses are of great importance.

摘要

背景

卵巢甲状腺肿是一种特殊类型的卵巢皮样囊肿,约占所有皮样肿瘤的 2-3%。良性卵巢甲状腺肿可能表现为远处转移,称为腹膜甲状腺肿,这使其在生物学上类似于恶性肿瘤,在有限的病例中已有报道,但从未在怀孕期间发现。

病例介绍

我们报告了一位有右侧卵巢甲状腺肿囊肿切除术病史的患者。在怀孕期间,再次发现盆腔有非特异性临床表现的肿块。在剖宫产术中,发现对侧卵巢有结节播散的卵巢甲状腺肿,病理显示肿块为甲状腺滤泡性卵巢甲状腺肿。

讨论和结论

复发性良性卵巢甲状腺肿伴卵巢外播散是一种罕见的侵袭性临床表现,不同于恶性肿瘤。强调对可疑肿块进行充分评估和完整切除非常重要。

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Struma ovarii and peritoneal strumosis during pregnancy.妊娠卵巢甲状腺肿和腹腔甲状腺肿。
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本文引用的文献

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Malignant struma ovarii harboring a unique NRAS mutation: case report and review of the literature.卵巢恶性甲状腺肿伴独特 NRAS 突变:病例报告及文献复习。
Hormones (Athens). 2017 Jul;16(3):322-327. doi: 10.14310/horm.2002.1750.
2
Treatment and follow-up of malignant struma ovarii: Regarding two cases.恶性卵巢甲状腺肿的治疗与随访:附两例报告
Gynecol Oncol Rep. 2016 Jun 8;17:56-9. doi: 10.1016/j.gore.2016.05.014. eCollection 2016 Aug.
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Papillary thyroid cancer located in malignant struma ovarii with omentum metastasis: a case report and review of the literature.
Front Oncol. 2025 May 15;15:1487812. doi: 10.3389/fonc.2025.1487812. eCollection 2025.
4
Struma Ovarii during Pregnancy.妊娠期卵巢甲状腺肿
Diagnostics (Basel). 2024 Jun 1;14(11):1172. doi: 10.3390/diagnostics14111172.
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Giant Benign Struma Ovarii with High-Grade Fever, Elevated CA 125, and Hormonal Function in an Adolescent Patient.青少年患者的巨大良性卵巢甲状腺肿伴高热、CA 125升高及激素功能异常
Children (Basel). 2023 May 11;10(5):856. doi: 10.3390/children10050856.
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Clinical Characteristics, Treatment, and Outcomes of Peritoneal Strumosis: A Report of Three Cases and Systematic Review.腹膜甲状腺肿的临床特征、治疗及结局:三例报告及系统评价
Diagnostics (Basel). 2023 Apr 28;13(9):1581. doi: 10.3390/diagnostics13091581.
7
Highly Differentiated Follicular Carcinoma of Ovarian Origin: A Systematic Review of the Literature.卵巢来源高分化滤泡性癌:文献系统综述。
Curr Oncol. 2022 Nov 23;29(12):9105-9116. doi: 10.3390/curroncol29120712.
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J Ovarian Res. 2022 Jun 14;15(1):71. doi: 10.1186/s13048-022-01007-y.
位于伴有大网膜转移的恶性卵巢甲状腺肿中的乳头状甲状腺癌:一例报告并文献复习
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