Pfister M, Fischer L
Dozentur für Neuraltherapie, Universität Bern, KIKOM, Inselspital, Bern.
Praxis (Bern 1994). 2009 Mar 4;98(5):247-57. doi: 10.1024/1661-8157.98.5.247.
Two female patients were referred to us with a complex regional pain syndrome (CRPS) of the upper limb. One patient developed a CRPS type 1 after a radius fracture, the other presented a CRPS type 2 after a wrist trauma with a nerve injury of N. ulnaris. Both patients had progressive pain in spite of medical treatment (NSAID, Gabapentine, Calcitonine), physiotherapy, occupational therapy and osteopathy. In addition to pain they also showed the typical autonomic symptoms like oedema, hyperhidrosis, disturbances of skin colour and temperature and a severely limited motility of wrist and fingers. The clinical symptoms of both types of CRPS are identical and not restricted to the peripheral nerve distribution. The sympathetic nerve system is not only involved in the pain mechanism with reflectory processes in the segment and with the sympathetic afferent coupling, it also takes part in the neuroplasticity and in the neurogenic inflammation. The logical therapeutic intervention is therefore to normalize the hyperactivity of the sympathetic nerve systems with local anaesthetics. This regulation is done with injections to the stellate ganglion if upper limbs are affected (affections of lower limbs are treated with injections to the lumbar sympathetic trunk). Repeated injections to the stellate ganglion caused immediate improvement of pain and other symptoms in both patients.
两名女性患者因上肢复杂性区域疼痛综合征(CRPS)前来就诊。一名患者在桡骨骨折后患上1型CRPS,另一名患者在腕部外伤并伴有尺神经损伤后出现2型CRPS。尽管接受了药物治疗(非甾体抗炎药、加巴喷丁、降钙素)、物理治疗、职业治疗和整骨疗法,两名患者仍有进行性疼痛。除疼痛外,她们还表现出典型的自主神经症状,如水肿、多汗、皮肤颜色和温度异常以及手腕和手指活动严重受限。两种类型的CRPS临床症状相同,且不限于周围神经分布。交感神经系统不仅通过节段性反射过程和交感传入耦合参与疼痛机制,还参与神经可塑性和神经源性炎症。因此,合理的治疗干预是用局部麻醉药使交感神经系统的过度活动正常化。如果上肢受影响,通过向星状神经节注射来进行这种调节(下肢受影响则通过向腰交感干注射来治疗)。对星状神经节进行反复注射后,两名患者的疼痛和其他症状立即得到改善。