用于潜伏性单纯疱疹病毒再激活并伴有外周病毒脱落的可靠体内模型。
Reliable in vivo model for latent herpes simplex virus reactivation with peripheral virus shedding.
作者信息
Nesburn A B, Green M T, Radnoti M, Walker B
出版信息
Infect Immun. 1977 Mar;15(3):772-5. doi: 10.1128/iai.15.3.772-775.1977.
Abstract
A long-sought laboratory model, a reliable system for in vivo reactivization of latent herpes simplex infection with peripheral shedding of active virus, is present. Results demonstrate that surgical stimulation of latently infected rabbit trigeminal ganglia induces peripheral release of infectious herpes simplex virus. Virus could be cultured from the tear film in 83% of the stimulated animals' eyes within 48 h.
摘要
一种长期寻找的实验室模型，即一种可靠的系统，可用于使潜伏的单纯疱疹感染在体内重新激活并伴有活性病毒的外周性排出，现已出现。结果表明，对潜伏感染的兔三叉神经节进行手术刺激可诱导传染性单纯疱疹病毒的外周释放。在48小时内，83%的受刺激动物的眼睛泪膜中可培养出病毒。
相似文献
1
Reliable in vivo model for latent herpes simplex virus reactivation with peripheral virus shedding.用于潜伏性单纯疱疹病毒再激活并伴有外周病毒脱落的可靠体内模型。
Infect Immun. 1977 Mar;15(3):772-5. doi: 10.1128/iai.15.3.772-775.1977.
2
In vivo reactivation of herpes simplex virus in rabbit trigeminal ganglia: electrode model.兔三叉神经节中单纯疱疹病毒的体内再激活：电极模型
Infect Immun. 1981 Oct;34(1):69-74. doi: 10.1128/iai.34.1.69-74.1981.
3
Therapeutic immunization with a mixture of herpes simplex virus 1 glycoprotein D-derived “asymptomatic” human CD8+ T-cell epitopes decreases spontaneous ocular shedding in latently infected HLA transgenic rabbits: association with low frequency of local PD-1+ TIM-3+ CD8+ exhausted T cells.用单纯疱疹病毒1型糖蛋白D衍生的“无症状”人CD8 + T细胞表位混合物进行治疗性免疫可减少潜伏感染的HLA转基因兔的自发性眼部排毒：与局部PD-1 + TIM-3 + CD8 +耗竭性T细胞的低频率相关。
J Virol. 2015 Jul;89(13):6619-32. doi: 10.1128/JVI.00788-15.
4
Herpes Simplex Virus 1 Infection of Tree Shrews Differs from That of Mice in the Severity of Acute Infection and Viral Transcription in the Peripheral Nervous System.单纯疱疹病毒1型感染树鼩在急性感染严重程度及外周神经系统病毒转录方面与小鼠不同。
J Virol. 2015 Oct 28;90(2):790-804. doi: 10.1128/JVI.02258-15. Print 2016 Jan 15.
5
Effect of immunization and immunosuppression on induced ocular shedding and recovery of herpes simplex virus in infected rabbits.免疫和免疫抑制对感染兔单纯疱疹病毒诱导的眼部分泌及病毒恢复的影响。
Exp Eye Res. 1987 Sep;45(3):375-83. doi: 10.1016/s0014-4835(87)80124-0.
6
CXCL10/CXCR3-Dependent Mobilization of Herpes Simplex Virus-Specific CD8 T and CD8 T Cells within Infected Tissues Allows Efficient Protection against Recurrent Herpesvirus Infection and Disease.CXCL10/CXCR3依赖性动员感染组织内的单纯疱疹病毒特异性CD8 T细胞和CD4 T细胞可有效预防复发性疱疹病毒感染和疾病。
J Virol. 2017 Jun 26;91(14). doi: 10.1128/JVI.00278-17. Print 2017 Jul 15.
7
Infectious Herpes Simplex Virus in the Brain Stem Is Correlated with Reactivation in the Trigeminal Ganglia.脑干中的感染性单纯疱疹病毒与三叉神经节中的再激活有关。
J Virol. 2019 Apr 3;93(8). doi: 10.1128/JVI.02209-18. Print 2019 Apr 15.
8
[Tissue of origin of herpes simplex virus type 1 reactivated in tear film].[在泪膜中重新激活的1型单纯疱疹病毒的组织起源]
Nippon Ganka Gakkai Zasshi. 1994 May;98(5):419-22.
9
The effect of trigeminal nerve and ganglion manipulation on recurrence of ocular herpes simplex in rabbits.三叉神经及神经节推拿对兔单纯疱疹性角膜炎复发的影响
Invest Ophthalmol. 1976 Sep;15(9):726-31.
10
Quantitation of herpes simplex virus type 1 DNA and latency-associated transcripts in rabbit trigeminal ganglia demonstrates a stable reservoir of viral nucleic acids during latency.对兔三叉神经节中1型单纯疱疹病毒DNA和潜伏相关转录本的定量分析表明，在潜伏期间病毒核酸存在稳定的储存库。
J Virol. 1996 May;70(5):3137-41. doi: 10.1128/JVI.70.5.3137-3141.1996.
引用本文的文献
1
A comparison of herpes simplex virus type 1 and varicella-zoster virus latency and reactivation.1型单纯疱疹病毒与水痘-带状疱疹病毒潜伏及再激活的比较
J Gen Virol. 2015 Jul;96(Pt 7):1581-602. doi: 10.1099/vir.0.000128. Epub 2015 Mar 20.
2
Rabbit and mouse models of HSV-1 latency, reactivation, and recurrent eye diseases.单纯疱疹病毒1型潜伏、激活及复发性眼部疾病的兔和小鼠模型
J Biomed Biotechnol. 2012;2012:612316. doi: 10.1155/2012/612316. Epub 2012 Oct 2.
3
Modification of bacterial serum susceptibility by rifampin.利福平对细菌血清敏感性的影响
Infect Immun. 1980 Jun;28(3):923-6. doi: 10.1128/iai.28.3.923-926.1980.
4
Inability of various immune mechanisms to establish in vitro latent infection in sensory neurons infected by HSV-1. Brief report.多种免疫机制无法在被单纯疱疹病毒1型（HSV-1）感染的感觉神经元中建立体外潜伏感染。简要报告。
Arch Virol. 1984;79(1-2):123-30. doi: 10.1007/BF01314310.
5
Thymidine kinase-deficient herpes simplex virus type 2 genital infection in guinea pigs.豚鼠中胸苷激酶缺陷型单纯疱疹病毒2型生殖器感染
J Virol. 1985 Aug;55(2):322-8. doi: 10.1128/JVI.55.2.322-328.1985.
6
Herpes simplex virus ocular infections: current concepts of acute, latent and reactivated disease.单纯疱疹病毒眼部感染：急性、潜伏性和再激活疾病的当前概念
Trans Am Ophthalmol Soc. 1990;88:727-96.
7
Persistence in herpes simplex virus infections.单纯疱疹病毒感染的持续性。
Postgrad Med J. 1978 Sep;54(635):603-12. doi: 10.1136/pgmj.54.635.603.
8
Uptake of horseradish peroxidase in sensory nerve terminals of mouse trigeminal nerve.小鼠三叉神经感觉神经末梢中辣根过氧化物酶的摄取
Acta Neuropathol. 1979 May 15;46(3):191-6. doi: 10.1007/BF00690843.
9
Contralateral facial palsy in a case of cervical zoster.一例带状疱疹患者出现对侧面瘫。
J Neurol. 1977 Dec 1;217(1):75-8. doi: 10.1007/BF00316319.
本文引用的文献
1
SOMATOTOPIC ORGANIZATION OF TRIGEMINAL-GANGLION NEURONES.三叉神经节神经元的躯体定位组织
Arch Neurol. 1964 Dec;11:593-602. doi: 10.1001/archneur.1964.00460240025003.
2
Recurrent cutaneous herpes simplex in hairless mice.无毛小鼠复发性皮肤单纯疱疹
Infect Immun. 1974 Sep;10(3):471-4. doi: 10.1128/iai.10.3.471-474.1974.
3
Recovery of herpes simplex virus from human sacral ganglions.从人骶神经节中分离出单纯疱疹病毒。
N Engl J Med. 1974 Oct 17;291(16):828-30. doi: 10.1056/NEJM197410172911606.
4
Persistent herpes simplex virus infection in rabbit trigeminal ganglia.兔三叉神经节中的持续性单纯疱疹病毒感染
Lab Invest. 1974 Feb;30(2):230-40.
5
Latent herpes simplex virus in the central nervous system of rabbits and mice.兔和小鼠中枢神经系统中的潜伏性单纯疱疹病毒。
J Exp Med. 1973 Sep 1;138(3):740-4. doi: 10.1084/jem.138.3.740.
6
Recovery of herpes-simplex virus from human trigeminal ganglions.从人三叉神经节中分离出单纯疱疹病毒。
N Engl J Med. 1973 Mar 29;288(13):648-50. doi: 10.1056/NEJM197303292881303.
7
Latent herpes simplex virus. Isolation from rabbit trigeminal ganglia between episodes of recurrent ocular infection.潜伏性单纯疱疹病毒。复发性眼部感染发作期间从兔三叉神经节中分离得到。
Arch Ophthalmol. 1972 Oct;88(4):412-7. doi: 10.1001/archopht.1972.01000030414012.
8
Long-term poly I:C in experimental chronic ocular herpes simplex infection.实验性慢性眼部单纯疱疹感染中的长期聚肌胞苷酸
Am J Ophthalmol. 1971 Oct;72(4):821-6. doi: 10.1016/0002-9394(71)90024-9.
9
Recurrence of herpes simplex virus in rabbit eyes: results of a three-year study.兔眼单纯疱疹病毒复发：一项为期三年的研究结果
Invest Ophthalmol. 1969 Jun;8(3):346-50.
10
Recurrent herpes in the rabbit and man.兔和人类的复发性疱疹。
Science. 1967 Jun 23;156(3782):1628-9. doi: 10.1126/science.156.3782.1628.
Zotero 插件