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[精神分裂症复发的前驱症状]

[Prodromes of schizophrenia recurrence].

作者信息

Bottai T, Cotton I, Drigeard A, Vaglio V

机构信息

Service de Psychiatrie Générale de Martigues 13G24, Hôpital du Vallon, BP 248, Centre Hospitalier de Martigues, 13698 Martigues cedex.

出版信息

Encephale. 2009 Jan;35 Suppl 1:S33-40. doi: 10.1016/S0013-7006(09)75530-7.

Abstract

Schizophrenic disorders are chronic disorders usually characterized by relapses alternating with periods of remission. A better understanding of the course of schizophrenic disorders is available with the models of psychotic vulnerability and the neurodevelopmental hypothesis. The relapses have numerous severe aspects, clinical, biological and conduct to a bad prognosis. A relapse prevention constitutes a major issue in regard of public health. A relapse prevention is possible with identification of relapse prodromal signs (or early signs of relapse). The relapse prodromal signs are often aspecific but remain stable in each patient. These relapse prodromal signs are similar to the initial prodromal signs, as well as in symptomatology than as their chronologic apparition. Specific psychoeducation strategy allows for each patient to learn its own stressful events and its own prodromal signs of relapse, as well as onset of each prodromal symptoms. A pilot study conducts to a psychoeducative program of relapse prevention centered on learning about prodromal symptoms and validation of a relapse prodromal signs questionnaire.

摘要

精神分裂症是一种慢性疾病,通常表现为复发与缓解期交替出现。通过精神病易感性模型和神经发育假说,可以更好地理解精神分裂症的病程。复发具有许多严重的方面,包括临床、生物学方面,并且预后不良。预防复发是公共卫生方面的一个主要问题。通过识别复发前驱症状(或复发早期迹象)可以预防复发。复发前驱症状通常不具有特异性,但在每个患者中保持稳定。这些复发前驱症状与初始前驱症状相似,在症状学以及出现时间上都是如此。特定的心理教育策略使每个患者能够了解自己的应激事件、复发前驱症状以及每种前驱症状的发作情况。一项试点研究开展了一项以了解前驱症状和验证复发前驱症状问卷为中心的预防复发心理教育项目。

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