血液透析患者的睡眠障碍与抑郁症密切相关。
Sleep disturbance in haemodialysis patients is closely related to depression.
作者信息
Paparrigopoulos Thomas, Theleritis Christos, Tzavara Chara, Papadaki Antonia
机构信息
First Department of Psychiatry, Athens University Medical School, Eginition Hospital, Athens, Greece.
出版信息
Gen Hosp Psychiatry. 2009 Mar-Apr;31(2):175-7. doi: 10.1016/j.genhosppsych.2008.09.016. Epub 2008 Oct 28.
OBJECTIVE
To investigate the relationship between depression and disturbed sleep in haemodialysis patients (HP), and its relative contribution in the development of reported sleep problems.
METHOD
A total of 101 patients suffering from end-stage renal disease (ESRD) were assessed through the Athens Insomnia Scale (AIS) for potential sleep problems. Anxiety and depression were evaluated with the Hospital Anxiety and Depression Scale (HADS), and their health-related quality of life and functional status were assessed through the Short Form-36 questionnaire (SF-36). Socio-demographic, anthropometric and clinical data along with a series of biochemical measures were also collected.
RESULTS
Multiple logistic regression analysis showed that the independent predictors associated with insomnia in ESRD patients were female sex (OR=7.58) and depression as measured by the HADS (OR=2.59).
CONCLUSION
Incorporating a standard assessment and eventually treatment of depressive symptoms into the care provided to haemodialysis patients might improve psychological well-being, insomnia and quality of life, and, consequently, reduce mortality risk in this population.
目的
探讨血液透析患者（HP）中抑郁与睡眠障碍之间的关系，及其在报告的睡眠问题发生发展中的相对作用。
方法
通过雅典失眠量表（AIS）对总共101例终末期肾病（ESRD）患者进行潜在睡眠问题评估。使用医院焦虑抑郁量表（HADS）评估焦虑和抑郁状况，并通过简明健康状况调查问卷（SF-36）评估其健康相关生活质量和功能状态。还收集了社会人口统计学、人体测量学和临床数据以及一系列生化指标。
结果
多因素logistic回归分析显示，与ESRD患者失眠相关的独立预测因素为女性（OR = 7.58）以及通过HADS测量的抑郁（OR = 2.59）。
结论
将抑郁症状的标准评估及最终治疗纳入血液透析患者的护理中，可能会改善其心理健康、失眠状况和生活质量，从而降低该人群的死亡风险。
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