1例格雷夫斯病合并汉坦病毒感染

A case of Graves' disease combined with hantaan virus infection.

作者信息

Jin Heung Yong, Kang Seon Mee, Kim So Young, Park Ji Hyun, Baek Hong Sun, Park Tae Sun

机构信息

Division of Endocrinology & Metabolism, Department of Internal Medicine and Research Institute of Clinical Medicine, Chonbuk National University, College of Medicine, Jeonju, Korea.

出版信息

J Korean Med Sci. 2009 Feb;24(1):158-61. doi: 10.3346/jkms.2009.24.1.158. Epub 2009 Feb 28.

DOI:10.3346/jkms.2009.24.1.158

PMID:19270831

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2650990/

Abstract

Graves' disease (GD) is generally presented by thyrotoxicosis with hyperthyroidism, and it is an organ-specific autoimmune disease induced by thyroid-stimulating hormone receptor autoantibodies. However, among diverse etiologies, viral infections have been suggested to trigger or to be involved in the pathogenesis of GD. Hantaan virus infection causing hemorrhagic fever with renal syndrome (HFRS) is common in South Korea and its pathogenesis is suggested to be an immunologic mechanism. We have experienced a patient who was diagnosed as HFRS with thyrotoxicosis. So we herein report the case as GD combined with the hantaan virus infection.

摘要

格雷夫斯病（GD）通常表现为甲状腺毒症伴甲状腺功能亢进，是一种由促甲状腺激素受体自身抗体诱导的器官特异性自身免疫性疾病。然而，在多种病因中，病毒感染被认为可触发或参与GD的发病机制。在韩国，导致肾综合征出血热（HFRS）的汉坦病毒感染很常见，其发病机制被认为是一种免疫机制。我们遇到过一名被诊断为患有甲状腺毒症的HFRS患者。因此，我们在此报告该病例为合并汉坦病毒感染的GD。