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手术治疗的肺结核:埃塞俄比亚亚的斯亚贝巴提库尔安贝萨医院病例报告

Surgically treated pulmonary tuberculosis: report on cases from Tikur Anbessa Hospital, Addis Ababa, Ethiopia.

作者信息

Bekele Abebe, Ali Adem, Biluts Hagos

机构信息

Department of Surgery, Addis Ababa University, Faculty of Medicine.

出版信息

Ethiop Med J. 2008 Jul;46(3):261-6.

Abstract

BACKGROUND

The treatment of pulmonary tuberculosis has evolved through multiples of treatment modalities including pulmonary surgery. In Ethiopia, though the disease is very common, there is no information regarding the patterns of surgically treated pulmonary tuberculosis and its outcome.

OBJECTIVE AND STUDY DESIGN

A retrospective clinical study was conducted to investigate the patterns and outcomes of surgically treated cases of pulmonary tuberculosis. Data was collected from the clinical records of all patients operated at the chest surgery unit with a confirmed diagnosis of pulmonary tuberculosis at the Tikur Anbessa teaching specialized referral hospital (26).

RESULT

Twenty-six patients were admitted for surgery, 80.8% of these patients were males. The mean duration of illness before presenting to the hospital was 27.6 months. Cough and hemoptysis were the two most common presenting symptoms, occurring in 26 (100%) and 24 (92.3%). The most common feature seen in chest x-rays was a completely destroyed lung tissue in 10 (38.5%). The parts of the lung commonly involved were the left side in 16 (61.5%) and the upper lobes in 14 (53.8%). The Sputum examination for acid-fast tubercle bacilli tested positive for 24 (92.3%) of the patients. The most frequent indications for surgery were severe hemoptysis for 12 (46.2%), radiographic evidence of destroyed lung for 5 (19.2%) and strong evidence for Aspergilloma for 3 (11.5%). The most frequently performed procedure were left upper lobectomy in 10 (38%), left pneumonectomy in 7 (26.7%) and right pneumonectomy in 7 (26.7%). Nine significant (34.6%) complications occurred in the postoperative period, the commonest being postoperative pneumonia in 4 (15.4%). Two (7.7%) of the patients died. During the follow-up period six patients developed significant late postoperative complications.

CONCLUSION

In the Ethiopian setting, though anti-tuberculous chemotherapy is the standard treatment for pulmonary tuberculosis in a majority of patients, there are still definite indications in which surgical management plays a vital role.

摘要

背景

肺结核的治疗已经历了多种治疗方式的演变,包括肺部手术。在埃塞俄比亚,尽管该疾病非常常见,但尚无关于手术治疗肺结核的模式及其结果的信息。

目的和研究设计

进行了一项回顾性临床研究,以调查手术治疗肺结核病例的模式和结果。数据收集自提库尔·安贝萨教学专科医院胸外科确诊为肺结核的所有手术患者的临床记录(26例)。

结果

26例患者接受手术治疗,其中80.8%为男性。入院前的平均病程为27.6个月。咳嗽和咯血是最常见的首发症状,分别有26例(100%)和24例(92.3%)出现。胸部X光片中最常见的特征是10例(38.5%)肺组织完全破坏。肺部常见受累部位为左侧16例(61.5%),上叶14例(53.8%)。24例(92.3%)患者痰涂片抗酸杆菌检测呈阳性。最常见的手术指征是严重咯血12例(46.2%)、肺部破坏的影像学证据5例(19.2%)和曲霉菌瘤的有力证据3例(11.5%)。最常进行的手术是左上叶切除术10例(38%)、左全肺切除术7例(26.7%)和右全肺切除术7例(26.7%)。术后发生9例严重(34.6%)并发症,最常见的是术后肺炎4例(15.4%)。2例(7.7%)患者死亡。在随访期间,6例患者出现了严重的术后晚期并发症。

结论

在埃塞俄比亚的情况下,尽管抗结核化疗是大多数肺结核患者的标准治疗方法,但仍有明确的指征表明手术治疗起着至关重要的作用。

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