Sharpe J A, Ranalli P J
Division of Neurology, Toronto Hospital, University of Toronto, Ontario, Canada.
Acta Otolaryngol Suppl. 1991;481:194-8. doi: 10.3109/00016489109131379.
The vertical vestibulo-ocular reflex (VOR) and its visual enhancement and cancellation were measured in patients with focal midbrain lesions that caused paralysis of upward, or upward and downward saccades. VOR gain was reduced in darkness during active vertical head pitch at frequencies from 0.25 to 2 Hz. Visual enhancement of the reflex by fixating a stationary target was subnormal upward and downward. Cancellation of the VOR was defective in both vertical directions during eye-head tracking. The VOR showed abnormal phase lead of the eyes in darkness, indicating that pretectal midbrain damage impairs the integration of eye velocity commands.
对患有局灶性中脑病变导致向上或向上和向下扫视麻痹的患者，测量了垂直前庭眼反射（VOR）及其视觉增强和消除情况。在0.25至2Hz频率的主动垂直头部俯仰过程中，黑暗中VOR增益降低。通过注视静止目标对反射进行的视觉增强在向上和向下方向均低于正常水平。在眼-头跟踪过程中，VOR在两个垂直方向的消除均存在缺陷。黑暗中VOR显示眼睛存在异常的相位超前，表明顶盖前区中脑损伤损害了眼速度指令的整合。
