Kiwerski Jerzy E
Department of Physiotherapy, Medical University of Warsaw, Poland.
Ortop Traumatol Rehabil. 2008 Nov-Dec;10(6):620-5.
Bone malignancies account for merely about 1.5% of all cancers, with a small percentage of these tumours developing in the cervical spine. However, the cervical spine is also the site of benign tumours and neoplasms involving not only bony tissue. Benign tumours do not metastasize but pose a threat to the spinal cord when located intrathecally. Even though such tumours do not represent malignancy, they are considered to be locally malignant. The most common cervical spine neoplasms are intradural tumours, usually extramedullary: neurofibromas, meningiomas or gliomas.Indications for surgery depend of the nature and location of the tumour and the consequences of tumour growth. Surgery is obviously necessary for intrathecal tumours compressing the spinal cord. The choice of surgical approach and manner of stabilisation depend primarily on the location of the lesion and the presence of spinal cord compression.Rehabilitation is indicated in all patients, but is particularly important, and at the same time difficult, when the growth of the tumour has resulted in neurological disturbances. The task is all the more difficult when in the presence of a massive and high spinal cord damage. Rehabilitation programmes should be designed individually for each patient and should account for the degree of paresis, stage of the underlying malignant disease, survival prognosis, disturbances in the function of other systems, apart from musculoskeletal apparatus, age of the patient, his or her commitment to treatment and other factors.The treatment of malignant neoplasms is usually associated with an unfavourable outcome. However, combination drug treatments, radiation therapy and surgery with subsequent rehabilitation will often prolong survival, ameliorate suffering and improve patients' quality of life.
骨恶性肿瘤仅占所有癌症的约1.5%,其中一小部分肿瘤发生在颈椎。然而,颈椎也是良性肿瘤和肿瘤样病变的好发部位,不仅涉及骨组织。良性肿瘤不会转移,但当位于鞘内时会对脊髓构成威胁。尽管这类肿瘤并非恶性,但被认为具有局部侵袭性。最常见的颈椎肿瘤是硬膜内肿瘤,通常位于髓外:神经纤维瘤、脑膜瘤或胶质瘤。手术指征取决于肿瘤的性质、位置以及肿瘤生长的后果。对于压迫脊髓的鞘内肿瘤,手术显然是必要的。手术入路和稳定方式的选择主要取决于病变的位置以及脊髓压迫的情况。所有患者都需要康复治疗,但当肿瘤生长导致神经功能障碍时,康复治疗尤为重要且同时具有挑战性。当存在严重且高位的脊髓损伤时,这项任务就更加困难。康复计划应针对每位患者单独设计,并应考虑肌无力程度、潜在恶性疾病的阶段、生存预后、除肌肉骨骼系统外其他系统的功能障碍、患者年龄、患者对治疗的依从性以及其他因素。恶性肿瘤的治疗通常预后不佳。然而,联合药物治疗、放射治疗和手术以及随后的康复治疗往往会延长生存期、减轻痛苦并提高患者的生活质量。