Van Aken Benoit
Department of Civil and Environmental Engineering, West Virginia University, Morgantown, WV 26506, USA.
Curr Opin Biotechnol. 2009 Apr;20(2):231-6. doi: 10.1016/j.copbio.2009.01.011. Epub 2009 Mar 9.
Phytoremediation of organic pollutants, such as explosives, is often a slow and incomplete process, potentially leading to the accumulation of toxic metabolites that can be further introduced into the food chain. During the past decade, plants have been genetically modified to overcome the inherent limitations of plant detoxification capabilities, following a strategy similar to the development of transgenic crop. Bacterial genes encoding enzymes involved in the breakdown of explosives, such as nitroreductase and cytochrome P450, have been introduced in higher plants, resulting in significant enhancement of plant tolerance, uptake, and detoxification performances. Transgenic plants exhibiting biodegradation capabilities of microorganisms bring the promise of an efficient and environmental-friendly technology for cleaning up polluted soils.
对爆炸物等有机污染物进行植物修复往往是一个缓慢且不彻底的过程,这可能导致有毒代谢产物的积累,而这些代谢产物可能会进一步进入食物链。在过去十年中,人们采用了类似于转基因作物开发的策略,对植物进行基因改造,以克服植物解毒能力的固有局限性。编码参与爆炸物分解的酶(如硝基还原酶和细胞色素P450)的细菌基因已被导入高等植物中,从而显著提高了植物的耐受性、吸收能力和解毒性能。具有微生物生物降解能力的转基因植物为清理污染土壤带来了一种高效且环保的技术前景。