Simpson D J, Price A J, Gulati A, Murray D W, Gill H S
Nuffield Department of Orthopaedic Surgery, University of Oxford, Oxford, OX3 7LD, UK.
Med Eng Phys. 2009 Sep;31(7):752-7. doi: 10.1016/j.medengphy.2009.02.004. Epub 2009 Mar 10.
Unexplained pain is an important complication of both total knee replacement and unicompartmental knee replacement. After unicompartmental knee replacement the most common site for the pain is antero-medial over the proximal tibia. The reason for this is not clear; however it may be due to high bone strain. A validated finite element model of a proximal tibia implanted with a fully congruent unicompartmental knee replacement was used to investigate the effect that certain implantation parameters had on the surface strains of the tibia. The tibial tray was positioned neutrally, and also mal-aligned separately in the sagittal and coronal planes. Different amounts of tibial tray overhang and underhang, and different resection levels were modelled. All models were compared to an intact tibia and the strain on the exterior cortex compared for a peak load condition measured in-vivo during a step-up activity. Following implantation the bone strain in the proximal tibia increased by 40%. There were no comparable increases in strain with different amounts of mal-alignment in the sagittal plane. There was a comparable increase in strain with a tibial tray overhang of 3 mm or greater, and excessive varus mal-alignment. This study has demonstrated that there is a large increase in strain, antero-medially on the proximal tibia, following implantation with a unicompartmental knee replacement. This may be the cause of antero-medial pain. As the bone remodels over time this strain will decrease, which probably explains why the pain usually settles within 12 months after surgery. However, certain errors in implantation result in strain values that might lead to degenerative remodelling and/or increased micro-damage of the bone; this may explain why the pain progressively worsens in some cases.
不明原因疼痛是全膝关节置换术和单髁膝关节置换术的重要并发症。单髁膝关节置换术后,最常见的疼痛部位是胫骨近端的前内侧。其原因尚不清楚;然而,这可能是由于高骨应变所致。利用一个植入完全匹配的单髁膝关节置换物的胫骨近端验证有限元模型,来研究某些植入参数对胫骨表面应变的影响。胫骨托处于中立位置,并且分别在矢状面和冠状面进行了位置不良排列。模拟了不同程度的胫骨托悬垂和内悬,以及不同的截骨水平。将所有模型与完整胫骨进行比较,并针对在逐步活动期间体内测量的峰值负荷条件,比较外侧皮质上的应变。植入后,胫骨近端的骨应变增加了40%。矢状面不同程度的位置不良排列并未导致应变有类似增加。胫骨托悬垂3毫米或更大以及过度内翻位置不良排列时,应变有类似增加。本研究表明,植入单髁膝关节置换物后,胫骨近端前内侧的应变大幅增加。这可能是前内侧疼痛的原因。随着时间推移骨会重塑,这种应变将会降低,这可能解释了为什么疼痛通常在术后12个月内缓解。然而,某些植入错误会导致应变值可能引发骨的退行性重塑和/或微损伤增加;这可能解释了为什么在某些情况下疼痛会逐渐加重。