Luyckx Thomas, Bori Edoardo, Saldari Rachele, Fiore Sara, Altamore Virginia, Innocenti Bernardo
Department of Orthopedic Surgery AZ Delta Roeselare Belgium.
BEAMS Department (Bio Electro and Mechanical Systems), École Polytechnique de Bruxelles Université Libre de Bruxelles Bruxelles Belgium.
J Exp Orthop. 2024 Oct 26;11(4):e70053. doi: 10.1002/jeo2.70053. eCollection 2024 Oct.
Unicompartmental knee arthroplasty (UKAs) are available in the market as fixed- and mobile-bearing (FB and MB) and can be characterised by a different set of design parameters in terms of geometries, materials and surgical approaches, with overall good clinical outcomes. However, clear biomechanical evidence concerning the consequences of variations of these features on knee biomechanics is still lacking; therefore, the present study aims to perform a sensitivity analysis to see which outcomes are affected by these variations.
For both MB-UKA and FB-UKA, five design and surgical parameters were defined (bearing insert thickness, tibial component material, implant components friction coefficient, antero-posterior slope angle and level of tibial bone resection). Two control models were defined based on standard configurations for both implants. Finite element analysis was chosen to perform this study, and different parameter combinations (216 models in total) were implemented and tested at both 0° and 90° of flexion, using a previously validated finite element knee model. The results were then evaluated in terms of bone and polyethylene Von Mises stress and tibio-femoral contact area.
Bearing thickness, tibial bone cut and slope angle were found to be the most sensitive parameters for both types of UKAs. Specifically, changes in these parameters in the FB-UKA appeared to induce more significant variations in the polyethylene insert (both in terms of polyethylene stress and contact area), while in the MB-UKA, these changes influenced bone stress distribution more.
Surgical parameters returned to have a more significant influence than material and friction variations; furthermore, the outcomes most affected by parameter variations were the insert-related ones for FB-UKA while for the MB-UKA were the ones regarding tibial bone stresses.
Not Applicable.
单髁膝关节置换术(UKA)在市场上有固定平台和活动平台(FB和MB)两种类型,其在几何形状、材料和手术方式等方面具有不同的设计参数组合,总体临床效果良好。然而,关于这些特征变化对膝关节生物力学影响的明确生物力学证据仍然缺乏;因此,本研究旨在进行敏感性分析,以确定哪些结果会受到这些变化的影响。
对于MB-UKA和FB-UKA,定义了五个设计和手术参数(承重垫片厚度、胫骨部件材料、植入部件摩擦系数、前后倾斜角度和胫骨骨切除水平)。基于两种植入物的标准配置定义了两个对照模型。本研究选择有限元分析,使用先前验证的有限元膝关节模型,在0°和90°屈曲状态下对不同参数组合(共216个模型)进行实施和测试。然后根据骨和聚乙烯的冯·米塞斯应力以及胫股接触面积对结果进行评估。
发现承重厚度、胫骨截骨和倾斜角度是两种类型UKA最敏感的参数。具体而言,FB-UKA中这些参数的变化似乎会在聚乙烯垫片上引起更显著的变化(在聚乙烯应力和接触面积方面),而在MB-UKA中,这些变化对骨应力分布的影响更大。
手术参数的影响比材料和摩擦变化更为显著;此外,受参数变化影响最大的结果,对于FB-UKA是与垫片相关的结果,而对于MB-UKA则是与胫骨骨应力相关的结果。
不适用。