Moses Robert G, Barker Megan, Winter Meagan, Petocz Peter, Brand-Miller Jennie C
Illawarra Diabetes Service, South Eastern Sydney and Illawarra Area Health Service, Wollongong, New South Wales, Australia.
Diabetes Care. 2009 Jun;32(6):996-1000. doi: 10.2337/dc09-0007. Epub 2009 Mar 11.
A low-glycemic index diet is effective as a treatment for individuals with diabetes and has been shown to improve pregnancy outcomes when used from the first trimester. A low-glycemic index diet is commonly advised as treatment for women with gestational diabetes mellitus (GDM). However, the efficacy of this advice and associated pregnancy outcomes have not been systematically examined. The purpose of this study was to determine whether prescribing a low-glycemic index diet for women with GDM could reduce the number of women requiring insulin without compromise of pregnancy outcomes.
All women with GDM seen over a 12-month period were considered for inclusion in the study. Women (n = 63) were randomly assigned to receive either a low-glycemic index diet or a conventional high-fiber (and higher glycemic index) diet.
Of the 31 women randomly assigned to a low-glycemic index diet, 9 (29%) required insulin. Of the women randomly assigned to a higher-glycemic index diet, a significantly higher proportion, 19 of 32 (59%), met the criteria to commence insulin treatment (P = 0.023). However, 9 of these 19 women were able to avoid insulin use by changing to a low-glycemic index diet. Key obstetric and fetal outcomes were not significantly different.
Using a low-glycemic index diet for women with GDM effectively halved the number needing to use insulin, with no compromise of obstetric or fetal outcomes.
低升糖指数饮食对糖尿病患者是一种有效的治疗方法,且已表明从孕早期开始使用可改善妊娠结局。低升糖指数饮食通常被建议用于治疗妊娠期糖尿病(GDM)女性。然而,该建议的疗效及相关妊娠结局尚未得到系统研究。本研究的目的是确定为GDM女性开具低升糖指数饮食处方是否能减少需要使用胰岛素的女性数量,同时不影响妊娠结局。
研究纳入了在12个月期间就诊的所有GDM女性。63名女性被随机分配接受低升糖指数饮食或传统高纤维(及高升糖指数)饮食。
随机分配到低升糖指数饮食组的31名女性中,9名(29%)需要胰岛素治疗。随机分配到高升糖指数饮食组的女性中,有更高比例(32名中的19名,59%)符合开始胰岛素治疗的标准(P = 0.023)。然而,这19名女性中有9名通过改为低升糖指数饮食避免了使用胰岛素。关键的产科和胎儿结局无显著差异。
对GDM女性使用低升糖指数饮食可有效将需要使用胰岛素的人数减半,且不影响产科或胎儿结局。