Beldie Luiza-Andreea, Dica Cristina-Camelia, Moța Maria, Pirvu Bianca-Florentina, Burticală Marilena-Alexandra, Mitrea Adina, Clenciu Diana, Efrem Ion Cristian, Vladu Beatrice Elena, Timofticiuc Diana Cristina Protasiewicz, Roșu Maria Magdalena, Gheonea Theodora Claudia, Amzolini Anca Maria, Moța Eugen, Vladu Ionela Mihaela
Department of Diabetes, Nutrition and Metabolic Diseases, County Clinical Emergency Hospital of Craiova, 200642 Craiova, Romania.
Doctoral School, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Nutrients. 2024 Nov 29;16(23):4131. doi: 10.3390/nu16234131.
Recent studies have revealed that dysbiosis, defined as alterations in gut microbiota, plays an important role in the development and the progression of many non-communicable diseases, including metabolic disorders, such as type 2 diabetes mellitus and gestational diabetes mellitus (GDM). The high frequency of GDM makes this disorder an important public health issue, which needs to be addressed in order to reduce both the maternal and fetal complications that are frequently associated with this disease. The studies regarding the connections between gut dysbiosis and GDM are still in their early days, with new research continuously emerging. This narrative review seeks to outline the mechanisms through which a healthy diet that protects the gut microbiota is able to prevent the occurrence of GDM, thus providing medical nutritional therapeutic perspectives for the management of GDM.
最近的研究表明，肠道微生物群的改变所定义的生态失调在许多非传染性疾病的发生和发展中起着重要作用，这些疾病包括代谢紊乱，如2型糖尿病和妊娠期糖尿病（GDM）。GDM的高发病率使这种疾病成为一个重要的公共卫生问题，为了减少与该疾病经常相关的母婴并发症，需要解决这一问题。关于肠道生态失调与GDM之间联系的研究仍处于早期阶段，新的研究不断涌现。这篇叙述性综述旨在概述保护肠道微生物群的健康饮食能够预防GDM发生的机制，从而为GDM的管理提供医学营养治疗的观点。
