Remzi Feza H, Fazio Victor W, Kirat Hasan T, Wu James S, Lavery Ian C, Kiran Ravi P
Department of Colorectal Surgery, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Dis Colon Rectum. 2009 Feb;52(2):198-204. doi: 10.1007/DCR.0b013e31819ad4b6.
: This study evaluated outcomes of patients with abdominal salvage operations for failed ileal pouch-anal anastomosis.
: Patients undergoing laparotomy for ileoanal pouch salvage were reviewed from a prospectively maintained pouch database and records.
: From 1983 to 2007, 241 abdominal reconstructions were performed. The median follow-up was 5 years (range, 0.04-20.8). Diagnoses before primary ileal pouch-anal anastomosis were ulcerative colitis in 187, familial adenomatous polyposis in 22, indeterminate colitis in 20, Crohn's disease in 9, and other in 3. The most common indications for salvage were fistula (n = 67), leak (n = 65), stricture (n = 42) pouch dysfunction (n = 40), pelvic abscess (n = 25). Seventy-one cases had a new pouch constructed. One hundred and seventy cases had the original pouch salvaged. Twenty-nine cases had either pouch excision or ileostomy without pouch excision the result of failure after reconstruction. To assess functional results and quality of life, patients with reconstruction were matched to those with a primary ileal pouch-anal anastomosis. Significantly higher proportions of patients with reconstruction reported seepage during daytime (P = 0.002), at night (P = 0.015), and daytime pad usage (P = 0.02). Other parameters and quality of life were similar between groups.
: Repeat abdominal surgery was a good alternative for pouch failure. Functional and quality of life outcomes were encouraging.
本研究评估了因回肠储袋肛管吻合术失败而接受腹部挽救手术患者的治疗结果。
从一个前瞻性维护的储袋数据库和记录中回顾了因回肠储袋挽救而接受剖腹手术的患者。
1983年至2007年期间,共进行了241例腹部重建手术。中位随访时间为5年(范围为0.04 - 20.8年)。初次回肠储袋肛管吻合术前的诊断为:溃疡性结肠炎187例,家族性腺瘤性息肉病22例,不确定性结肠炎20例,克罗恩病9例,其他3例。挽救手术最常见的指征是瘘管(n = 67)、渗漏(n = 65)、狭窄(n = 42)、储袋功能障碍(n = 40)、盆腔脓肿(n = 25)。71例患者构建了新的储袋。170例患者保留了原储袋。29例患者进行了储袋切除或未切除储袋的回肠造口术,这是重建失败的结果。为了评估功能结果和生活质量,将接受重建手术的患者与初次行回肠储袋肛管吻合术的患者进行匹配。接受重建手术的患者报告白天渗漏(P = 0.002)、夜间渗漏(P = 0.015)和白天使用护垫情况(P = 0.02)的比例明显更高。两组之间的其他参数和生活质量相似。
重复腹部手术是储袋失败的一种良好替代方案。功能和生活质量结果令人鼓舞。