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颅内脂肪瘤:神经影像学的临床表现及临床意义

Intracranial lipomas: clinical appearances on neuroimaging and clinical significance.

作者信息

Jabot Geraldine, Stoquart-Elsankari Souraya, Saliou Guillaume, Toussaint Patrick, Deramond Hervé, Lehmann Pierre

机构信息

Neuroradiology, Amiens University Hospital, 1 place Victor Pauchet, 80054, Amiens Cedex 1, France.

出版信息

J Neurol. 2009 Jun;256(6):851-5. doi: 10.1007/s00415-009-5087-5. Epub 2009 Mar 12.

Abstract

Intracranial lipomas are rare congenital malformations which are neither hematomas nor true neoplasms. They result from the abnormal persistence and maldifferentiation of the meninx primitiva. The majority of such lesions occur near the midline. Around 55% of intracranial lipomas are associated with brain malformations of varying severity. Although they are usually an incidental finding, symptomatic intracranial lipomas are sometimes observed. Surgical excision may result in high morbidity and mortality due to the highly vascular nature of intracranial lipomas and the latter's strong adhesion to the surrounding tissue and is very rarely indicated.

摘要

颅内脂肪瘤是罕见的先天性畸形,既不是血肿也不是真正的肿瘤。它们是由原始脑膜的异常存留和分化异常所致。此类病变大多发生在中线附近。约55%的颅内脂肪瘤伴有不同程度的脑畸形。虽然它们通常是偶然发现的,但有时也会观察到有症状的颅内脂肪瘤。由于颅内脂肪瘤血管丰富且与周围组织粘连紧密,手术切除可能导致高发病率和死亡率,因此很少进行手术。

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