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[转移性恶性脉络膜黑色素瘤:一例长达18年姑息性手术治疗的病例报告]

[Metastatic malignant choroidal melanoma: a case report about 18 years with palliative operative treatment].

作者信息

Prietzel T, Haferkorn I, Macher A, Schumann E, von Salis-Soglio G, Aigner T

机构信息

Orthopädische Klinik und Poliklinik, Universität, Liebigstrasse 20, 04103, Leipzig, Deutschland.

出版信息

Orthopade. 2009 Mar;38(3):278-82. doi: 10.1007/s00132-009-1409-7.

DOI:10.1007/s00132-009-1409-7
PMID:19280174
Abstract

Bone metastases are found in 29% of patients with metastatic malignant choroidal melanoma, which is associated with poor prognosis. However there are several reports about prolonged survival. The unusual case of a patient is described, who suffered from a melanoma with orbital invasion and survived more than 18 years. Metastases were found 12 years after initial therapy. Three palliative operations made a survival of further 7 years with high quality of life possible. Therefore moderately palliative operations are recommended in case of metastatic malignant choroidal melanoma.

摘要

在转移性恶性脉络膜黑色素瘤患者中,29%会发生骨转移,这与预后不良相关。然而,有几篇关于生存期延长的报道。本文描述了一例不寻常的病例,该患者患有眼眶侵袭性黑色素瘤,存活了18年以上。初始治疗12年后发现转移。三次姑息性手术使患者又存活了7年,且生活质量较高。因此,对于转移性恶性脉络膜黑色素瘤患者,建议进行适度的姑息性手术。

相似文献

1
[Metastatic malignant choroidal melanoma: a case report about 18 years with palliative operative treatment].[转移性恶性脉络膜黑色素瘤:一例长达18年姑息性手术治疗的病例报告]
Orthopade. 2009 Mar;38(3):278-82. doi: 10.1007/s00132-009-1409-7.
2
Treatment considerations for primary uveal melanoma with choroidal metastasis to the fellow eye.原发性葡萄膜黑色素瘤伴对侧眼脉络膜转移的治疗考量
Semin Ophthalmol. 2007 Jul-Sep;22(3):175-7. doi: 10.1080/08820530701501055.
3
Simultaneous metastases of cutaneous malignant melanoma to conjunctiva and choroid.皮肤恶性黑色素瘤同时转移至结膜和脉络膜。
Br J Ophthalmol. 2000 Aug;84(8):930-1. doi: 10.1136/bjo.84.8.928b.
4
Endoresection for choroidal melanoma: palliative or curative intent?
Br J Ophthalmol. 2008 Aug;92(8):1015-6. doi: 10.1136/bjo.2008.145805.
5
Malignant melanoma of skin and eye in the same family: more than a coincidence?
Bull Soc Belge Ophtalmol. 1989;231:149-55.
6
Choroidal malignant melanoma with liver metastasis before enucleation.眼球摘除术前伴有肝转移的脉络膜恶性黑色素瘤。
Ann Ophthalmol. 1982 Aug;14(8):789-91, 794-6.
7
[Late metastasis development in two cases of small choroidal melanoma].
Cesk Slov Oftalmol. 2013 Aug;69(3):134-7.
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Palliative surgery for skeletal metastases from melanoma in the scaphoid--a critical case report appraisal.掌骨转移性黑色素瘤的姑息性手术——一个关键病例报告评价。
J Plast Reconstr Aesthet Surg. 2012 Aug;65(8):1111-5. doi: 10.1016/j.bjps.2012.01.019. Epub 2012 Mar 3.
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Diffuse primary malignant melanoma after prior primary cutaneous malignant melanoma.既往有原发性皮肤恶性黑色素瘤后出现的弥漫性原发性恶性黑色素瘤。
Arch Ophthalmol. 1980 Jul;98(7):1261-4. doi: 10.1001/archopht.1980.01020040113017.
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[Orbital Exenteration in Patient with Metastatic Choroidal Melanoma - a Case Report].[转移性脉络膜黑色素瘤患者的眼眶内容剜除术——病例报告]
Cesk Slov Oftalmol. 2016 Fall;72(3):92-96.

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