Jao Tun, Liu Hon-Man, Tang Sung-Chun, Jeng Jiann-Shing
Stroke Center & Department of Neurology, National Taiwan University Hospital, Taipei, Taiwan.
Acta Neurol Taiwan. 2008 Dec;17(4):243-7.
The posterior inferior cerebellar artery (PICA) is frequently involved in dissection of the vertebral artery (VA); however, isolated PICA dissection has rarely been reported. A 37-year-old man experienced acute and progressive drowsiness, vertigo, occipital headache, vomiting, and ataxia. There was no precedent trauma or chiropractic manipulation. Neurologically, he had dysmetria of the left extremities. His NIHSS score was 3. Brain magnetic resonance imaging showed an acute cerebellar infarct in the left PICA territory. Magnetic resonance angiography showed a faint signal adjacent to the junction of the left VA and PICA, suggesting a vascular shadow. Catheter angiography showed focal stenosis with a post-stenotic fusiform aneurysmal dilatation of the left proximal PICA that was highly suggestive of dissection with pseudoaneurysm formation. He was treated with clopidogrel and was free of neurological symptoms 3 months after the stroke event. Isolated PICA dissection may be considered in patients with PICA territory infarct or subarachnoid hemorrhage. Treatment depends on the manifestations; ruptured dissecting aneurysms are often treated with surgery or embolization, and infarcts are usually treated with antithrombotic agents.
小脑后下动脉(PICA)常累及椎动脉(VA)夹层;然而,孤立性PICA夹层鲜有报道。一名37岁男性出现急性进行性嗜睡、眩晕、枕部头痛、呕吐和共济失调。无前驱创伤或整脊治疗史。神经系统检查发现其左上肢辨距不良。美国国立卫生研究院卒中量表(NIHSS)评分为3分。脑部磁共振成像显示左侧PICA供血区急性小脑梗死。磁共振血管造影显示左侧VA与PICA交界处附近有微弱信号,提示血管影。导管血管造影显示左侧PICA近端局限性狭窄,狭窄后呈梭形动脉瘤样扩张,高度提示夹层伴假性动脉瘤形成。给予氯吡格雷治疗,卒中事件3个月后无神经症状。对于PICA供血区梗死或蛛网膜下腔出血患者,可考虑孤立性PICA夹层。治疗取决于临床表现;破裂的夹层动脉瘤常采用手术或栓塞治疗,梗死通常采用抗血栓药物治疗。