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包膜警告综合征:一例报告。

Capsular warning syndrome: report of a case.

作者信息

Teng Hao-Wen, Hong Chi-Tzong

机构信息

Department of Neurology, Taipei Medical University-Wan Fang Hospital, Taiwan.

出版信息

Acta Neurol Taiwan. 2008 Dec;17(4):248-52.

PMID:19280869
Abstract

The "capsular warning syndrome" (CWS) is characterized by recurrent stereotypical episodes of motor and/or sensory dysfunction without cortical signs. CWS is a clinically well recognized entity, and carries a significant risk of capsular infarct. The ischemia is most likely ascribable to hemodynamic changes in diseased small penetrating vessels. Treatment remains controversial and none has been proven effective. We described a 66-year-old man having 15 episodes of stereotypical transient ischemic attack within four days. The findings of the diffusion-weighted image showed abnormalities confined concurrently to the left lateral thalamus, posterior globus pallidus, and posterior corona radiata while the internal capsule was spared. Theses findings suggest involvement of the territory of anterior choroidal artery. We also documented changes in the pattern of attacks after initiation of intravenous urokinase.

摘要

“包膜警告综合征”(CWS)的特征是反复出现刻板的运动和/或感觉功能障碍发作,而无皮质体征。CWS是一种临床上已得到充分认识的病症,且有发生包膜梗死的重大风险。缺血很可能归因于病变小穿支血管的血流动力学变化。治疗仍存在争议,且尚无已被证明有效的治疗方法。我们描述了一名66岁男性,在四天内发生了15次刻板的短暂性脑缺血发作。弥散加权成像的结果显示异常同时局限于左侧丘脑外侧、苍白球后部和放射冠后部,而内囊未受累。这些发现提示脉络膜前动脉供血区受累。我们还记录了静脉注射尿激酶后发作模式的变化。

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引用本文的文献

1
Capsular warning syndrome and its clinical awareness and therapeutic approach: two case reports and a systematic review of the literature.包膜警告综合征及其临床认识与治疗方法:两例病例报告及文献系统综述
Front Neurol. 2023 May 16;14:1177660. doi: 10.3389/fneur.2023.1177660. eCollection 2023.
2
Capsular warning syndrome: clinical analysis and treatment.胶囊警告综合征:临床分析与治疗。
BMC Neurol. 2019 Nov 13;19(1):285. doi: 10.1186/s12883-019-1522-0.
3
Population-based study of capsular warning syndrome and prognosis after early recurrent TIA.
基于人群的胶囊警告综合征研究及早期复发性 TIA 后的预后。
Neurology. 2012 Sep 25;79(13):1356-62. doi: 10.1212/WNL.0b013e31826c1af8. Epub 2012 Sep 12.
4
Capsular warning syndrome caused by middle cerebral artery stenosis.大脑中动脉狭窄致囊袋警告综合征。
J Neurol Sci. 2010 Sep 15;296(1-2):115-20. doi: 10.1016/j.jns.2010.06.003. Epub 2010 Jul 8.