Teng Hao-Wen, Hong Chi-Tzong
Department of Neurology, Taipei Medical University-Wan Fang Hospital, Taiwan.
Acta Neurol Taiwan. 2008 Dec;17(4):248-52.
The "capsular warning syndrome" (CWS) is characterized by recurrent stereotypical episodes of motor and/or sensory dysfunction without cortical signs. CWS is a clinically well recognized entity, and carries a significant risk of capsular infarct. The ischemia is most likely ascribable to hemodynamic changes in diseased small penetrating vessels. Treatment remains controversial and none has been proven effective. We described a 66-year-old man having 15 episodes of stereotypical transient ischemic attack within four days. The findings of the diffusion-weighted image showed abnormalities confined concurrently to the left lateral thalamus, posterior globus pallidus, and posterior corona radiata while the internal capsule was spared. Theses findings suggest involvement of the territory of anterior choroidal artery. We also documented changes in the pattern of attacks after initiation of intravenous urokinase.
“包膜警告综合征”(CWS)的特征是反复出现刻板的运动和/或感觉功能障碍发作,而无皮质体征。CWS是一种临床上已得到充分认识的病症,且有发生包膜梗死的重大风险。缺血很可能归因于病变小穿支血管的血流动力学变化。治疗仍存在争议,且尚无已被证明有效的治疗方法。我们描述了一名66岁男性,在四天内发生了15次刻板的短暂性脑缺血发作。弥散加权成像的结果显示异常同时局限于左侧丘脑外侧、苍白球后部和放射冠后部,而内囊未受累。这些发现提示脉络膜前动脉供血区受累。我们还记录了静脉注射尿激酶后发作模式的变化。