Marsilia Giuseppina Marino, Boscaino Amedeo, La Mura Anna, Ceriello Antonio, De Ritis Rosaria
Departments of Pathology, Italy.
Int J Surg Pathol. 2010 Dec;18(6):537-9. doi: 10.1177/1066896908329589. Epub 2009 Mar 11.
We report a case of hepatic angiomyolipoma associated to a small bowel schwannoma in a 40-years old woman. Both lesions were asyntomatic. Histologically, hepatic angiomyolipoma showed oncocytic features and scanty adipose tissue, the tumor cells expressed desmin, smooth muscle actin, S-100 protein and HMB45. The tumor cells of intramural small intestinal mass were positive for S-100 protein and GFAP and negative for CD117, CD34 and desmin. To the best of our knowledge, no case of hepatic angiomyolipoma has been previously reported in association with intestinal schwannoma.
我们报告了一例40岁女性的肝血管平滑肌脂肪瘤合并小肠神经鞘瘤病例。两个病灶均无症状。组织学上，肝血管平滑肌脂肪瘤显示嗜酸性细胞特征且脂肪组织稀少，肿瘤细胞表达结蛋白、平滑肌肌动蛋白、S-100蛋白和HMB45。壁内小肠肿物的肿瘤细胞S-100蛋白和胶质纤维酸性蛋白呈阳性，而CD117、CD34和结蛋白呈阴性。据我们所知，此前尚无肝血管平滑肌脂肪瘤与肠道神经鞘瘤相关的病例报道。
