艾滋病毒对痰涂片诊断结核病效用的影响。
The impact of HIV on the usefulness of sputum smears for the diagnosis of tuberculosis.
作者信息
Long R, Scalcini M, Manfreda J, Jean-Baptiste M, Hershfield E
机构信息
Department of Medicine, Hospital Albert Schweitzer, Haiti.
出版信息
Am J Public Health. 1991 Oct;81(10):1326-8. doi: 10.2105/ajph.81.10.1326.
Abstract
In a developing country, 289 patients were examined for active pulmonary mycobacterial disease (sputum smear and culture) and HIV infection (serology) to compare the sensitivity and positive predictive value of sputum smears for diagnosing pulmonary tuberculosis in patients with and without antibodies to HIV. Seventy-nine percent of HIV-seronegative vs 66% of HIV-seropositive patients with positive cultures for Mycobacterium tuberculosis were smear positive (P less than .05), and a positive sputum smear predicted the presence of M. tuberculosis in 90% of HIV seronegative vs 80% of HIV seropositive patients (P less than .05). In our opinion, HIV did not significantly compromise the diagnostic utility of the sputum smear.
摘要
在一个发展中国家，对289例患者进行了活动性肺部分枝杆菌病（痰涂片和培养）及HIV感染（血清学）检查，以比较痰涂片在诊断有和没有HIV抗体的患者肺结核时的敏感性和阳性预测值。结核分枝杆菌培养阳性的HIV血清阴性患者中79%痰涂片阳性，而HIV血清阳性患者中这一比例为66%（P<0.05）；在HIV血清阴性患者中，痰涂片阳性预测结核分枝杆菌存在的准确率为90%，而在HIV血清阳性患者中为80%（P<0.05）。我们认为，HIV并未显著影响痰涂片的诊断效用。
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