Akpunonu B E, Ansel G, Kaurich J D, Savolaine E R, Campbell E W, Myles J L
Department of Internal Medicine, Medical College of Ohio, Toledo.
Am J Trop Med Hyg. 1991 Sep;45(3):390-8. doi: 10.4269/ajtmh.1991.45.390.
A case of zygomycosis involving the maxillary sinus in a normal host and mimicking paranasal malignancy is presented. Computed tomographic images showing destruction of adjoining bony structures and histologic features of fungi are described and presented. A successful outcome was achieved with amphotericin B irrigation and parenteral amphotericin B. Nasal biopsy should be advised by both radiologists and clinicians in all cases of lesions that look like malignancy in the sinus areas before a treatment modality is initiated.
本文报告一例正常宿主发生的累及上颌窦并酷似鼻窦恶性肿瘤的接合菌病。描述并展示了计算机断层扫描图像显示的相邻骨质结构破坏及真菌的组织学特征。通过两性霉素B冲洗和静脉注射两性霉素B取得了成功的治疗效果。对于所有鼻窦区域疑似恶性肿瘤的病变,在开始治疗前,放射科医生和临床医生均应建议进行鼻腔活检。