Brown S R, Shah I A, Grinstead M
Otolaryngology Section, Carl T. Hayden VA Medical Center, Phoenix, Arizona 85012, USA.
Am J Rhinol. 1998 Jul-Aug;12(4):289-92. doi: 10.2500/105065898781389994.
Mucormycosis is an uncommon fungal disease and one of the most fulminant infections known. This is the second report of rhinocerebral mucormycosis caused by Apophysomyces elegans, a newly recognized genus and species classified in the family Mucoraceae. The patient was a 54-year-old man being treated for a severe sinus infection with antibiotics and oral steroids. Recovery occurred in our patient after prompt surgical debridement and drainage of his maxillary sinuses. This case fits the reported characteristics of other A. elegans infections including warm climate, intimate contact with the soil, and an incubation period measured in days. Several reported cases indicate A. elegans can cause mucormycosis in immunocompetent individuals with no underlying medical problems.
毛霉病是一种罕见的真菌疾病，也是已知最迅猛的感染之一。这是由雅致犁头霉引起的鼻脑型毛霉病的第二例报告，雅致犁头霉是毛霉科一个新确认的属和种。患者为一名54岁男性，正在用抗生素和口服类固醇治疗严重的鼻窦感染。在对上颌窦进行及时的手术清创和引流后，我们的患者康复了。该病例符合其他雅致犁头霉感染报告的特征，包括温暖的气候、与土壤的密切接触以及以天计算的潜伏期。几例报告病例表明，雅致犁头霉可在没有潜在医疗问题的免疫功能正常个体中引起毛霉病。
