Zervomanolakis I, Ott H W, Müller J, Seeber B E, Friess S C, Mattle V, Virgolini I, Heute D, Wildt L
University Clinic of Gynecological Endocrinology and Reproductive Medicine, Department of Obstetrics and Gynecology, Medical University Innsbruck, Anichstrasse 35, A-6020 Innsbruck, Austria.
Eur J Obstet Gynecol Reprod Biol. 2009 May;144 Suppl 1:S45-9. doi: 10.1016/j.ejogrb.2009.02.012. Epub 2009 Mar 14.
Spermatozoa transport into uterus and fallopian tubes is directed to the side of the dominant follicle and seems to be controlled by the ipsilateral ovary. The objective of this study was to evaluate the temperature in the fallopian tubes as well as the concentrations of estradiol and progesterone in the utero-ovarian veins draining the ipsilateral ovary and compare these to the contralateral side of the uterus.
A prospective clinical study.
Academic-assisted reproductive technology program.
Temperature was measured in both oviducts of 10 patients each in the early phase as well as during the late follicular phase during the course of examination of tubal patency and function. Blood samples of the ovarian veins were obtained during hysterectomy in 10 premenopausal patients with regular menstrual cycles. Five of the women were in the early follicular phase and 5 were in the late follicular phase.
Late follicular phase temperature as well as concentrations of estradiol and progesterone were significantly higher in the ipsilateral tube and the utero-ovarian veins draining the ipsilateral ovary as compared to the contralateral side. No such differences were found during the early follicular phase of the cycle.
These data support our view that the uterus and fallopian tubes during the late follicular phase immediately before ovulation are composed of two functional units with different functional properties acting as a peristaltic pump resulting in increased transport of spermatozoa into the oviduct ipsilateral to the ovary bearing the dominant follicle and that this effect is mediated in part by the utero-ovarian countercurrent system.
精子向子宫和输卵管的运输指向优势卵泡一侧，似乎受同侧卵巢控制。本研究的目的是评估输卵管内的温度以及引流同侧卵巢的子宫卵巢静脉中雌二醇和孕酮的浓度，并将其与子宫的对侧进行比较。
一项前瞻性临床研究。
学术辅助生殖技术项目。
在检查输卵管通畅性和功能的过程中，对10例患者在卵泡早期和卵泡晚期分别测量双侧输卵管的温度。在10例月经周期规律的绝经前患者子宫切除术中采集卵巢静脉血样。其中5名女性处于卵泡早期，5名处于卵泡晚期。
与对侧相比，同侧输卵管以及引流同侧卵巢的子宫卵巢静脉在卵泡晚期的温度以及雌二醇和孕酮浓度显著更高。在月经周期的卵泡早期未发现此类差异。
这些数据支持我们的观点，即在排卵前的卵泡晚期，子宫和输卵管由两个具有不同功能特性的功能单元组成，它们作为蠕动泵，导致精子向携带优势卵泡的卵巢同侧输卵管的运输增加，并且这种作用部分由子宫卵巢逆流系统介导。
