补体介导的肿瘤生长：对癌症纳米技术和纳米药物的影响。
Complement-mediated tumour growth: implications for cancer nanotechnology and nanomedicines.
作者信息
Moghimi S M, Andresen T L
出版信息
Mol Immunol. 2009 May;46(8-9):1571-2. doi: 10.1016/j.molimm.2009.02.014. Epub 2009 Mar 14.
PMID:19286261
Abstract
The recent unexpected observation that complement activation helps tumour growth and progression has an important bearing on the future development of cancer nanomedicines for site-specific tumour targeting as these entities are capable of triggering complement. These issues are discussed and suggestions are provided for future design and development of safer and effective cancer nanomedicines.
摘要
最近意外观察到补体激活有助于肿瘤生长和进展，这对用于位点特异性肿瘤靶向的癌症纳米药物的未来发展具有重要影响，因为这些实体能够触发补体。本文讨论了这些问题，并为未来设计和开发更安全有效的癌症纳米药物提供了建议。
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