Hara Masumi, Izumida Yoshihiko, Sato Nobuhiro, Ohashi Ken, Osuga Jun-ichi, Tobe Kazuyuki, Tsukamoto Kazuhisa, Kadowaki Takashi
Department of Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Diabetes Res Clin Pract. 2009 Jun;84(3):e48-9. doi: 10.1016/j.diabres.2009.02.016. Epub 2009 Mar 14.
The patient was a 56-year-old man with type 2 diabetes and insulin allergy. He was administered glargine, which did not produce any allergic reactions, except for a small non-pruritic wheal. Thereafter, other insulin preparation could be administered. We consider this the first case of successful insulin desensitization by glargine administration.
该患者为一名56岁男性,患有2型糖尿病且对胰岛素过敏。他接受了甘精胰岛素治疗,除出现一个小的非瘙痒性风团外,未产生任何过敏反应。此后,可以给予其他胰岛素制剂。我们认为这是首例通过给予甘精胰岛素成功进行胰岛素脱敏的病例。