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通过给予门冬胰岛素和甘精胰岛素来使人体胰岛素及其类似物过敏脱敏。

Desensitization of allergy to human insulin and its analogs by administering insulin aspart and insulin glargine.

机构信息

Department of pharmacology, 3rd affiliated hospital, Soochow university, Jiangsu Changzhou, China.

出版信息

Ann Endocrinol (Paris). 2013 Feb;74(1):56-8. doi: 10.1016/j.ando.2012.11.005. Epub 2013 Jan 23.

DOI:10.1016/j.ando.2012.11.005
PMID:23351561
Abstract

Insulin allergy is a rare clinical situation. We report a 51-year-old patient with type 2 diabetes who required multiple daily insulin injections. The patient developed allergy to human regular insulin and insulin analogs (insulin aspart and insulin glargine), which was resolved by subcutaneous insulin desensitization.

摘要

胰岛素过敏是一种罕见的临床情况。我们报告了一位 51 岁的 2 型糖尿病患者,他需要每天多次注射胰岛素。该患者对人普通胰岛素和胰岛素类似物(门冬胰岛素和甘精胰岛素)产生过敏,通过皮下胰岛素脱敏得以解决。

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RAPID DESENSITIZATION WITH INTRAVENOUS INSULIN IN A PATIENT WITH DIABETIC KETOACIDOSIS AND INSULIN ALLERGY.
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Hypersensitivity reactions to human insulin analogs in insulin-naïve patients: a systematic review.初治患者对人胰岛素类似物的超敏反应:一项系统评价
Ther Adv Endocrinol Metab. 2018 Feb;9(2):53-65. doi: 10.1177/2042018817745484. Epub 2017 Dec 26.