Lew J K, Hutchinson R, Lin E S
Chinese University of Hong Kong, Department of Anaesthesia and Intensive Care, Prince of Wales Hospital, Shatin, NT.
Anaesthesia. 1991 Sep;46(9):719-21. doi: 10.1111/j.1365-2044.1991.tb09763.x.
Prothrombin time and activated partial thromboplastin time were measured in two groups of 30 patients each. Blood sampled from an arterial line after various discard volumes and from a central venous line were compared with direct venipuncture control samples. The arterial line flushing solution contained 1 unit of heparin per ml in group 1 and 2 units per ml in group 2. Our results confirmed that clotting studies carried out on blood samples from an arterial line or central venous line correlate well with those obtained from a venipuncture sample. The only exception was activated partial thromboplastin time in group 2 patients when the discard volume from the arterial line is only 2.5 ml above the deadspace volume of the connecting line. At least 5 ml of discard volume must be withdrawn before sampling, to obtain reliable results.
对两组各30名患者测量了凝血酶原时间和活化部分凝血活酶时间。将从动脉管路在不同弃血体积后采集的血液以及从中心静脉管路采集的血液与直接静脉穿刺对照样本进行比较。第1组动脉管路冲洗液每毫升含1单位肝素，第2组每毫升含2单位肝素。我们的结果证实，对动脉管路或中心静脉管路采集的血样进行的凝血研究与静脉穿刺样本获得的结果相关性良好。唯一的例外是第2组患者，当动脉管路的弃血体积仅比连接管的死腔体积多2.5毫升时，活化部分凝血活酶时间出现异常。采样前必须至少抽出5毫升弃血体积，以获得可靠结果。
