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呼肠孤病毒样病原体作为婴儿医院感染性腹泻的一个病因

Reovirus-like agent as a cause of nosocomial diarrhea in infants.

作者信息

Ryder R W, McGowan J E, Hatch M H, Palmer E L

出版信息

J Pediatr. 1977 May;90(5):698-702. doi: 10.1016/s0022-3476(77)81230-4.

DOI:10.1016/s0022-3476(77)81230-4
PMID:192867
Abstract

Surveillance for nosocomial diarrhea due to a reovirus-like agent was maintained on the pediatric wards of a large metropolitan hospital in January and February, 1976, during a large community outbreak of that illness. During this period, 30 (27%) of 111 children under surveillance were admitted for dehydration secondary to diarrhea; 21 (70%) of these 30 children had RLA in stool samples obtained at admission. Ten (17%) of the 60 children admitted without diarrhea, hence at risk of acquiring nosocomial RLA infection, contracted the illness. With human RLA as an antigen, no hospital personnel had serologic (complement fixation test) evidence of infection. Early attempts to control the diarrhea at home and in the outpatient department by the use of oral fluid rehydration, isolation of patients with severe symptoms requiring hospitalization, and strict attention by hospital personnel to hand washing between examination of patients may limit nosocomial spread of the disease.

摘要

1976年1月和2月,在一场大规模社区疾病暴发期间,一家大型都市医院的儿科病房对呼肠孤病毒样病原体引起的医院感染性腹泻进行了监测。在此期间,111名受监测儿童中有30名(27%)因腹泻继发脱水入院;这30名儿童中有21名(70%)在入院时采集的粪便样本中检测到呼肠孤病毒样病原体。60名未患腹泻而入院、因此有感染医院获得性呼肠孤病毒样病原体风险的儿童中有10名(17%)感染了该病。以人呼肠孤病毒样病原体作为抗原,没有医院工作人员有感染的血清学(补体结合试验)证据。早期尝试通过使用口服补液在家中和门诊控制腹泻,隔离需要住院治疗的重症患者,以及医院工作人员在检查患者之间严格注意洗手,可能会限制该病在医院内的传播。

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