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癌症患者疼痛的分类——一项系统的文献综述

Classification of pain in cancer patients--a systematic literature review.

作者信息

Knudsen A K, Aass N, Fainsinger R, Caraceni A, Klepstad P, Jordhøy M, Hjermstad M J, Kaasa S

机构信息

Pain and Palliation Research Group and Department of Cancer Research and Molecular Medicine, Faculty of Medicine, NTNU, Trondheim University Hospital, Trondheim, Norway.

出版信息

Palliat Med. 2009 Jun;23(4):295-308. doi: 10.1177/0269216309103125. Epub 2009 Mar 13.

DOI:10.1177/0269216309103125
PMID:19286741
Abstract

One of the aims of the European Palliative Care Research Collaborative (EPCRC) is to achieve consensus on a classification system for cancer pain. We performed a systematic literature review to identify existing classification systems and domains/items used to classify cancer patients with pain. In a systematic search in the databases Medline and Embase, covering 1986-2006, 692 hits were obtained. 92 papers were evaluated to address pain classification. Six standardised classification systems were identified; three of them systematically developed and partially validated. Both pain characteristics and patient characteristics relevant for cancer pain classification were included in the classification systems. All but one of the standardised systems aim at predicting treatment response or adequacy of treatment. Several domains and items used to describe cancer pain but not formally described as part of a classification system were also identified and systematized. The existing approaches to pain classification in cancer patients are different, mostly not thoroughly validated, and none is widely applied. An internationally accepted classification system for cancer pain could improve research and cancer pain management. This systematic review suggests a need for developing an international consensus on how to classify pain in cancer patients.

摘要

欧洲姑息治疗研究协作组(EPCRC)的目标之一是就癌症疼痛分类系统达成共识。我们进行了一项系统的文献综述,以确定现有的分类系统以及用于对癌症疼痛患者进行分类的领域/条目。在对1986年至2006年期间的Medline和Embase数据库进行的系统检索中,共获得692条结果。对92篇论文进行了评估以探讨疼痛分类问题。确定了六种标准化分类系统;其中三种是系统开发且部分经过验证的。分类系统中既包括与癌症疼痛分类相关的疼痛特征,也包括患者特征。除了一个标准化系统外,其他所有系统都旨在预测治疗反应或治疗的充分性。还确定并系统化了一些用于描述癌症疼痛但未被正式描述为分类系统一部分的领域和条目。目前癌症患者疼痛分类的方法各不相同,大多未经过充分验证,且没有一种得到广泛应用。一个国际认可的癌症疼痛分类系统可能会改善研究和癌症疼痛管理。这项系统综述表明,有必要就如何对癌症患者的疼痛进行分类达成国际共识。

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