Opperman C H, Chang S
J Nematol. 1990 Oct;22(4):481-8.
The sensitivity of acetylcholinesterases (ACHE) isolated from the plant-parasitic nematodes Meloidogyne arenaria, M. incognita, and Heterodera glycines and the free-living nematode Caenorhabditis elegans to carbamate and organophosphate nematicides was examined. The AChE from plant-parasitic nematode species were more sensitive to carbamate inhibitors than was AChE from C. elegans, but response to the organophosphates was approximately equivalent. The sulfur-containing phosphate nematicides were poor inhibitors of nematode acetylcholinesterase, but treatment with an oxidizing agent greatly improved inhibition. Behavioral bioassays with living nematodes revealed a poor relationship between enzyme inhibition and expression of symptoms in live nematodes.
研究了从植物寄生线虫南方根结线虫、爪哇根结线虫、大豆胞囊线虫以及自由生活线虫秀丽隐杆线虫中分离出的乙酰胆碱酯酶（ACHE）对氨基甲酸酯类和有机磷酸酯类杀线虫剂的敏感性。植物寄生线虫种类的ACHE对氨基甲酸酯类抑制剂的敏感性高于秀丽隐杆线虫的ACHE，但对有机磷酸酯类的反应大致相当。含硫的磷酸酯类杀线虫剂对线虫乙酰胆碱酯酶的抑制作用较差，但用氧化剂处理可大大提高抑制效果。对线虫进行的行为生物测定表明，酶抑制与活线虫症状表达之间的关系不明显。
