Division of Respiratory, Critical Care and Occupational Pulmonary Medicine, Department of Internal Medicine, University of Utah, Salt Lake City, UT 84132, USA.
Clin Rev Allergy Immunol. 2009 Dec;37(3):167-72. doi: 10.1007/s12016-009-8126-1. Epub 2009 Mar 17.
Airway smooth muscles of asthmatics tend to be hyperresponsive when provoked. The exaggerated bronchial constriction can be measured by the airflow limitation seen following bronchial provocation. Measuring bronchial hyperresponsiveness by broncho provocation testing is helpful in diagnosing and optimizing therapy. While numerous agents have been used to provoke a measurable airflow limitation, standardized protocols are available for only a few. This article aims to discuss the various methods that have been reported for bronchoprovocation testing.
哮喘患者的气道平滑肌在受到刺激时往往会过度反应。支气管激发试验可以测量到支气管收缩的过度程度,从而反映气道的受限情况。通过支气管激发试验来测量气道高反应性有助于诊断和优化治疗。虽然有许多药物已被用于引起可测量的气流受限,但只有少数药物有标准化的方案。本文旨在讨论已报道的各种支气管激发试验方法。