猪E血型系统中的新血型因子Es、Et及一个新等位基因Ebdgjmt（E16）

New blood group factors Es, Et and a new allele Ebdgjmt (E16) in the pig E blood group system.

作者信息

Hojný J, Hradecký J, Cwik S, Schmid D O

机构信息

Department of Genetics, Institute of Animal Physiology and Genetics, Czechoslovak Academy of Sciences, Libĕchov.

出版信息

Anim Genet. 1991;22(3):251-8. doi: 10.1111/j.1365-2052.1991.tb00675.x.

DOI:10.1111/j.1365-2052.1991.tb00675.x

PMID:1928831

Abstract

By immunizing a miniature sow a monovalent reagent (later designated anti-Es) was prepared, detecting an alternative antigen to the Ej. Blood group factors Ej and Es thus form the fifth genetically closed E subsystem. Analyses of selected raw sera containing anti-Ej led to the determination of a further Ej subgroup (designated Et) which is antithetical, mutually excluding with the blood factor Er. New blood factor Et is inherited by alleles Edeghjmnt (= E9) and (= E16). The investigation in pig breeds kept in CSFR indicated that allele Edeghjmnt occurs in Black and White Prestice breed (qE9 = 0.076 +/- 0.010) while allele Edeghjmnr (= E14) only in miniature pigs (qE9 = 0.147 +/- 0.011) and in wild pigs. In an élite herd of Swedish Landrace kept in CSFR a new complex allele Ebdgjmt (= E16) was found. Its frequency in the population studied was 0.058 +/- 0.022.

摘要

通过给一头小型母猪免疫制备了一种单价试剂（后来命名为抗-Es），该试剂可检测到与Ej不同的一种抗原。血型因子Ej和Es因此构成了第五个遗传封闭的E子系统。对含有抗-Ej的选定原始血清进行分析后，确定了另一个Ej亚组（命名为Et），它与血型因子Er相对立且相互排斥。新的血型因子Et由等位基因Edeghjmnt（= E9）和（= E16）遗传。在捷克斯洛伐克社会主义共和国饲养的猪品种中的调查表明，等位基因Edeghjmnt出现在黑白普雷斯蒂奇品种中（qE9 = 0.076 ± 0.010），而等位基因Edeghjmnr（= E14）仅出现在小型猪中（qE9 = 0.147 ± 0.011）和野猪中。在捷克斯洛伐克社会主义共和国饲养的瑞典长白猪的一个精英猪群中发现了一个新的复合等位基因Ebdgjmt（= E16）。其在所研究群体中的频率为0.058 ± 0.022。