Lu Yi, Gao Rui, Liao Zhuan, Hu Liang-Hao, Li Zhao-Shen
Department of Gastroenterology, Changhai Hospital, Second Military Medical University, 168 Changhai Road, Shanghai 200433, China.
World J Gastroenterol. 2009 Mar 14;15(10):1254-8. doi: 10.3748/wjg.15.1254.
To review the literature on capsule endoscopy (CE) for detecting esophageal varices using conventional esophagogastroduodenoscopy (EGD) as the standard.
A strict literature search of studies comparing the yield of CE and EGD in patients diagnosed or suspected as having esophageal varices was conducted by both computer search and manual search. Data were extracted to estimate the pooled diagnostic sensitivity and specificity.
There were seven studies appropriate for meta-analysis in our study, involving 446 patients. The pooled sensitivity and specificity of CE for detecting esophageal varices were 85.8% and 80.5%, respectively. In subgroup analysis, the pooled sensitivity and specificity were 82.7% and 54.8% in screened patients, and 87.3% and 84.7% in the screened/patients under surveillance, respectively.
CE appears to have acceptable sensitivity and specificity in detecting esophageal varices. However, data are insufficient to determine the accurate diagnostic value of CE in the screen/surveillance of patients alone.
以传统食管胃十二指肠镜检查（EGD）为标准，回顾关于胶囊内镜（CE）检测食管静脉曲张的文献。
通过计算机检索和手工检索，对比较CE和EGD在诊断或疑似患有食管静脉曲张患者中的检出率的研究进行严格的文献检索。提取数据以估计合并诊断敏感性和特异性。
我们的研究中有7项研究适合进行荟萃分析，涉及446例患者。CE检测食管静脉曲张的合并敏感性和特异性分别为85.8%和80.5%。在亚组分析中，筛查患者的合并敏感性和特异性分别为82.7%和54.8%，筛查/监测患者的合并敏感性和特异性分别为87.3%和84.7%。
CE在检测食管静脉曲张方面似乎具有可接受的敏感性和特异性。然而，数据不足以确定CE单独在筛查/监测患者中的准确诊断价值。
