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抑郁障碍患病率的社会不平等。

Social inequality in the prevalence of depressive disorders.

机构信息

Institute of Public Health Science, Copenhagen University, Centre for Health and Society, Øster Farimagsgade 5, Postbox 2099, 1014 Copenhagen K, Denmark.

出版信息

J Epidemiol Community Health. 2009 Jul;63(7):575-81. doi: 10.1136/jech.2008.082719. Epub 2009 Mar 16.

Abstract

BACKGROUND

Uncertainties exist about the strength of the relation between socioeconomic position and depressive disorders. The aim of this study was to investigate the association between education, occupation, employment and income and depressive disorders measured as minor and major depression, as well as antidepressant prescriptions.

METHODS

Data were collected from a Danish cross-sectional study collected year 2000, comprising 9254 subjects, 55% women, and aged 36-56 years. Register-based information on education, income and prescription were used.

RESULTS

The prevalence of major depression DSM-IV algorithm was 3.3% among men and women, whereas minor depression and prescriptions revealed statistically significant higher prevalence among females. A social gradient was found for all depressive end-points with the strongest estimates related to major depressive disorder (MDD). The associations were as follows: MDD and low education odds ratio (OR) 2.38 (CI 95% 1.68 to 3.37), MDD and non-employment OR 11.67 (CI 95% 8.06 to 16.89), MDD and low income OR 9.78 (CI 95% 6.49 to 14.74). Education only explained a minor part of the association between non-employment and depressive disorders and no associations were found between education and prescription. This indicates a strong two-way association between depression and non-employment, low-income respectively.

CONCLUSION

A social gradient in depressive disorders was found regardless of socioeconomic position being measured by education, occupation, employment or income. Severe socioeconomic consequences of depression are indicated by the fact that the associations with non-employment and low income were much stronger than the association with low education.

摘要

背景

社会经济地位与抑郁障碍之间的关系强度存在不确定性。本研究旨在调查教育程度、职业、就业和收入与抑郁障碍(包括轻度和重度抑郁以及抗抑郁药物处方)之间的关联。

方法

数据来自丹麦一项 2000 年进行的横断面研究,共纳入 9254 名年龄在 36-56 岁的研究对象,其中 55%为女性。研究使用了基于登记的教育程度、收入和处方信息。

结果

男性和女性的重度抑郁障碍(DSM-IV 算法)患病率为 3.3%,而轻度抑郁障碍和抗抑郁药物处方的患病率在女性中呈现出统计学上显著更高。所有抑郁终点均存在社会梯度,与重度抑郁障碍(MDD)相关的估计值最强。关联如下:MDD 与低教育程度的比值比(OR)为 2.38(95%可信区间 1.68-3.37),MDD 与非就业的 OR 为 11.67(95%可信区间 8.06-16.89),MDD 与低收入的 OR 为 9.78(95%可信区间 6.49-14.74)。教育程度仅解释了非就业与抑郁障碍之间关联的一小部分,而在教育程度与处方之间未发现关联。这表明抑郁与非就业、低收入之间存在着强烈的双向关联。

结论

无论社会经济地位是通过教育程度、职业、就业还是收入来衡量,都发现了抑郁障碍的社会梯度。抑郁与非就业和低收入之间的关联比与低教育程度之间的关联要强得多,这表明了严重的社会经济后果。

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