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[膝关节色素沉着绒毛结节性滑膜炎及关节镜检查结果]

[Knee ochronotic arthropathy and arthroscopic findings].

作者信息

Kural Cemal, Cetinus Ercan Mahmut, Kural Alev, Uğraş Ali Akin, Kaya Ibrahim

机构信息

Haseki Eğitim ve Araştirma Hastanesi, Ortopedi ve Travmatoloji Kliniği, Istanbul, Turkey.

出版信息

Acta Orthop Traumatol Turc. 2009 Jan-Feb;43(1):67-71. doi: 10.3944/AOTT.2009.067.

Abstract

Ochronotic arthropathy is a rare condition found in patients with alkaptonuria which is a hereditary metabolic disease associated with deposition of homogentisic acid derivatives in the articular cartilage, menisci, ligaments, and connective tissues due to homogentisic acid oxidase deficiency. These pigmentary changes are termed ochronosis. We presented a 50-year-old woman in whom arthroscopic examination of the right knee revealed brown-black discoloration of the articular cartilage and menisci leading to the diagnosis of alkaptonuria by further laboratory examinations.

摘要

褐黄病性关节病是一种罕见病症,见于患尿黑酸尿症的患者,尿黑酸尿症是一种遗传性代谢疾病,由于尿黑酸氧化酶缺乏,致使尿黑酸衍生物沉积于关节软骨、半月板、韧带及结缔组织中。这些色素沉着变化被称为褐黄病。我们报告了一名50岁女性,其右膝关节镜检查显示关节软骨和半月板呈棕黑色变色,经进一步实验室检查确诊为尿黑酸尿症。

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