双侧膝关节褐黄病性关节炎：一例报告
Ochronotic arthritis of bilateral knees: a case report.
作者信息
Xu Hang, Wang Jianzhao, Chen Fuying, Hong Zengchao, Zhang Xiaoyang, Ji Xiaohui, Shao Decheng
机构信息
Department of Sports Medicine, The Third Hospital of Hebei Medical University Shijiazhuang 050051, China.
Department of Operation Theater, The Third Hospital of Hebei Medical University Shijiazhuang 050051, China.
出版信息
Int J Clin Exp Med. 2015 May 15;8(5):8185-9. eCollection 2015.
Alkaptonuria ochronosis is a rare metabolic disease in which the body does not have enough enzyme called homogentisic acid oxidase. Due to the homogentisic acid oxidase deficiency, homogentisic acid accumulates in cartilage and connective tissues which leads to ochronotic arthritis. We reported a case of bilateral ochronotic arthritis verified by clinical presentation, imaging, arthroscopic and histological findings. The patient achieved a satisfying therapeutic outcome after arthroscopic debridement followed by intra-articular injection of sodium haluronate.
黑尿病性褐黄病是一种罕见的代谢性疾病，患者体内缺乏一种名为尿黑酸氧化酶的酶。由于尿黑酸氧化酶缺乏，尿黑酸在软骨和结缔组织中蓄积，进而导致褐黄病性关节炎。我们报告了一例经临床表现、影像学、关节镜及组织学检查确诊的双侧褐黄病性关节炎病例。该患者在接受关节镜清创术并关节腔内注射透明质酸钠后，取得了满意的治疗效果。
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