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Ionic strength-dependent structural transition of proteins at electrode surfaces.

作者信息

Palecek Emil, Ostatná Veronika

机构信息

Institute of Biophysics, Academy of Sciences of the Czech Republic, v.v.i., Královopolská 135, 612 65, Brno, Czech Republic.

出版信息

Chem Commun (Camb). 2009 Apr 7(13):1685-7. doi: 10.1039/b822274f. Epub 2009 Feb 17.

Abstract

Using constant current chronopotentiometry we showed that in 50 mM sodium phosphate (pH 7) bovine serum albumin and some other proteins were not significantly denatured at a bare mercury electrode while at higher phosphate concentrations they underwent electric field-driven denaturation on the electrode surface.

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