Aricò M, Pedroni E, Nespoli L, Viganò M, Porta F, Burgio G R
University Department of Paediatrics, IRCCS Policlinico S Matteo, Pavia, Italy.
Arch Dis Child. 1991 Aug;66(8):985-6. doi: 10.1136/adc.66.8.985.
A 10 year old child developed severe cardiomyopathy after combined, multicycle chemotherapy for Ewing's sarcoma and was treated by heart transplantation with good results. Long term azathioprine and cyclosporin caused only mild impairment of immune function and there were no recurrent infections, local recurrences of the tumour, or distant metastases.
一名10岁儿童在接受尤因肉瘤联合多周期化疗后出现严重心肌病,接受心脏移植治疗后效果良好。长期使用硫唑嘌呤和环孢素仅导致免疫功能轻度受损,且无反复感染、肿瘤局部复发或远处转移。