Shinji Akihiro, Hara Etsuo, Mukawa Kenji, Mochizuki Taro, Ohta Hiroshi, Yamamura Nobuyoshi, Oguchi Hisao, Yazawa Kazuyuki, Kajikawa Shoji, Nakamura Toshitsugu
Dept. of Gastroenterology, Suwa Red Cross Hospital.
Gan To Kagaku Ryoho. 2009 Mar;36(3):497-500.
A78-year-old female was admitted to our hospital with anorexia due to ascites. We were not able to diagnose by cytological diagnosis. For a definite diagnosis she underwent an open biopsy. Histological findings revealed observable papillary adenocarcinoma with psammoma body, carcinoma cells were positive for Ber-EP4 on immunostaining, and ovaries were normal. Thus, we made a diagnosis of peritoneal serous papillary adenocarcinoma. She was treated by intraperitoneal administration of CDDP(20 mg/day: day 1, every four weeks). Ascites vanished and CA125 was within the normal range. There was no recurrence after 3 years, but Virchow's lymph node metastasis occurred. The patient is still alive 12 months after metastasis with CDDP intraperitoneal administration.
一名78岁女性因腹水导致厌食症入住我院。我们无法通过细胞学诊断进行确诊。为明确诊断，她接受了开放性活检。组织学检查结果显示可见伴有砂粒体的乳头状腺癌，免疫染色显示癌细胞Ber-EP4呈阳性，卵巢正常。因此，我们诊断为腹膜浆液性乳头状腺癌。她接受了腹腔内注射顺铂（20毫克/天：第1天，每四周一次）的治疗。腹水消失，CA125在正常范围内。3年后无复发，但出现了魏尔啸淋巴结转移。转移后12个月，患者通过腹腔内注射顺铂仍然存活。
