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代谢综合征、心血管风险与亚临床动脉粥样硬化筛查

Metabolic syndrome, cardiovascular risk and screening for subclinical atherosclerosis.

作者信息

Malik Shaista, Wong Nathan D

机构信息

Division of Cardiology, University of California-Irvine Medical Center, 101 City Drive South, Orange, CA 92868, USA.

出版信息

Expert Rev Cardiovasc Ther. 2009 Mar;7(3):273-80. doi: 10.1586/14779072.7.3.273.

DOI:10.1586/14779072.7.3.273
PMID:19296765
Abstract

The metabolic syndrome is a clustering of risk factors known to promote or increase the risk of diabetes development and subsequent cardiovascular disease. Screening for subclinical atherosclerosis using new imaging technologies or novel biomarkers could help to further risk-stratify patients with metabolic syndrome. In particular, noninvasive imaging of carotid intima-media thickness and coronary artery calcium scoring seem to have promising prognostic value in identifying patients at high risk. Early identification could lead to improved patient or physician adherence to risk-reducing behaviors or interventions and improve clinical outcomes.

摘要

代谢综合征是一组已知会促进或增加糖尿病发生风险以及后续心血管疾病风险的危险因素。使用新的成像技术或新型生物标志物筛查亚临床动脉粥样硬化有助于对代谢综合征患者进行进一步的风险分层。特别是,颈动脉内膜中层厚度的无创成像和冠状动脉钙化评分在识别高危患者方面似乎具有良好的预后价值。早期识别可提高患者或医生对降低风险行为或干预措施的依从性,并改善临床结局。

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