Choi J-Y, Oh K, Kim B-J, Chung C-S, Koh S-B, Park K-W
Department of Neurology, Korea University Medical Centre, Korea University College of Medicine, Seoul, Republic of Korea.
Cephalalgia. 2009 Sep;29(9):953-9. doi: 10.1111/j.1468-2982.2008.01822.x. Epub 2009 Feb 27.
Photophobia is an important criterion for the diagnosis of migraine. However, several Asian epidemiological surveys about migraine have shown lesser prevalence of photophobia than that of Western studies. This discrepancy is probably caused by underestimation of photophobia due to inappropriate questioning of patients by physicians. To investigate this issue, we developed a questionnaire about photophobia and evaluated its usefulness in 103 patients with migraine. In phase 1 of the study, we found good repeatability of the questionnaire with a 0.826 kappa coefficient. In phase 2, the prevalence of photophobia from interviews and that from the questionnaire were compared. The prevalence of interview-documented photophobia was 51.5% and of questionnaire-documented photophobia 82.5% (P < 0.001). In phase 3, we attempted to make a short-form questionnaire with the same detection power of the questionnaire study. Two short-form questionnaires were identified as a useful method for detecting photophobia. The prevalence of photophobia could be underreported via interview, especially in Asian migraineurs. Using this questionnaire to test for photophobia, the diagnostic rate of photophobia and migraine could be improved.
畏光是偏头痛诊断的一项重要标准。然而，多项关于偏头痛的亚洲流行病学调查显示，畏光的患病率低于西方研究。这种差异可能是由于医生对患者的询问方式不当导致畏光被低估。为了研究这个问题，我们编制了一份关于畏光的问卷，并在103例偏头痛患者中评估了其效用。在研究的第一阶段，我们发现问卷具有良好的重复性，kappa系数为0.826。在第二阶段，比较了访谈记录的畏光患病率和问卷记录的畏光患病率。访谈记录的畏光患病率为51.5%，问卷记录的畏光患病率为82.5%（P<0.001）。在第三阶段，我们试图编制一份具有与问卷调查相同检测能力的简版问卷。两种简版问卷被确定为检测畏光的有效方法。通过访谈，畏光的患病率可能被低估，尤其是在亚洲偏头痛患者中。使用这份问卷检测畏光，可以提高畏光和偏头痛的诊断率。
