Aydınlar Elif Ilgaz, Bayır Buse Rahime Hasırcı, Dörtkol Ozan, Orhan Elif Kocasoy, Ekizoğlu Esme, Baykan Betül, Ertaş Mustafa
Department of Neurology, Acıbadem Mehmet Ali Aydınlar University School of Medicine, İstanbul, Turkey.
Department of Neurology, Haydarpaşa Numune Training and Research Hospital, İstanbul, Turkey.
Noro Psikiyatr Ars. 2023 Aug 10;60(3):236-244. doi: 10.29399/npa.28353. eCollection 2023.
The 12-item Utah Photophobia Symptom Impact Scale (UPSIS-12) is a questionnaire to assess the impact of photophobia on daily living during and outside migraine episodes. We aimed to translate UPSIS-12 and assess its usability in the Turkish cohort by analyzing internal consistency, reliability, and reproducibility.
In this multicenter prospective, descriptive study, 120 patients with migraine were recruited. The patients received the diagnosis of migraine without aura (MwoA) and migraine with aura (MwA) according to the International Classification of Headache Disorders 3rd edition. The scale was translated into Turkish, and the patients were evaluated by headache experts in two visits four weeks apart from each other.
The questionnaire showed highly correlated test-retest reliability (r=0.828). Cronbach alpha values of internal consistency revealed good to excellent results ranging from 0.78-0.82. There was a strong and positive correlation between self and physician-administered scales at both visits (r=0.964 and 0.985, respectively). The questionnaire was considered "well understood" by 95.6% of the patients. The average UPSIS-12 score of each visit was 25.8 and 26.9 (average standard deviation of 10.4). Subjects with MwoA (25.5±10.4) had remarkably lower mean scores compared to MwoA plus MwA (29.2±8.9) and MwA (32.9±9.4) (p=0.0167). Patients with high frequency migraine presented with a higher mean UPSIS-12 score than those with low frequency (31.3±9.5 and 24.7±9.8, respectively). It was noted that the mean UPSIS-12 scores of those with severe (29.4±9.4) and moderate ictal cutaneous allodynia (CA) (28.4±10.6) were higher than those without CA (22.0±9.3)(p=0.020).
The Turkish version of the UPSIS-12 questionnaire is a reliable tool and well-understood by the Turkish population. Patients with MwA, frequent migraine headache days and moderate to severe CA presented with higher scores. Given the independent burden of photophobia in migraineurs, the use of UPSIS-12 scale should be encouraged in Turkish population.
12项犹他畏光症状影响量表（UPSIS - 12）是一种用于评估畏光在偏头痛发作期间及发作之外对日常生活影响的问卷。我们旨在翻译UPSIS - 12，并通过分析内部一致性、可靠性和可重复性来评估其在土耳其人群中的可用性。
在这项多中心前瞻性描述性研究中，招募了120名偏头痛患者。根据《国际头痛疾病分类》第3版，这些患者被诊断为无先兆偏头痛（MwoA）和有先兆偏头痛（MwA）。该量表被翻译成土耳其语，患者由头痛专家进行两次评估，两次评估间隔四周。
问卷显示重测信度高度相关（r = 0.828）。内部一致性的Cronbach α值显示出良好到优秀的结果，范围为0.78 - 0.82。两次评估中，患者自评量表与医生评定量表之间均存在强正相关（分别为r = 0.964和0.985）。95.6%的患者认为问卷“易于理解”。每次评估的UPSIS - 12平均得分分别为25.8和26.9（平均标准差为10.4）。与无先兆偏头痛加有先兆偏头痛（29.2±8.9）和有先兆偏头痛（32.9±9.4）相比，无先兆偏头痛患者（25.5±10.4）的平均得分显著更低（p = 0.0167）。高频偏头痛患者的UPSIS - 12平均得分高于低频偏头痛患者（分别为31.3±9.5和24.7±9.8）。值得注意的是，有严重（29.4±9.4）和中度发作期皮肤异常性疼痛（CA）（28.4±10.6）患者的UPSIS - 12平均得分高于无CA患者（22.0±9.3）（p = 0.020）。
UPSIS - 12问卷的土耳其语版本是一种可靠的工具，并且土耳其人群易于理解。有先兆偏头痛、偏头痛发作天数频繁以及中度至重度皮肤异常性疼痛的患者得分更高。鉴于畏光在偏头痛患者中造成的独立负担，在土耳其人群中应鼓励使用UPSIS - 12量表。
