van Dijk J G, Haan J, Koenderink M, Roos R A
Department of Neurology, University Hospital Leiden, The Netherlands.
Arch Neurol. 1991 Oct;48(10):1083-4. doi: 10.1001/archneur.1991.00530220105028.
Autonomic nervous function was assessed in 11 patients with progressive supranuclear palsy, 26 patients with Parkinson's disease, matched for age, medications, disease severity, and disease duration, and 19 age-matched controls. Results of both parasympathetic (heart rate response to deep breathing and Valsalva maneuver) and sympathetic (blood pressure decrease on standing and increase on sustained handgrip) tests were abnormal in both patient groups. Abnormalities in the group of patients with progressive supranuclear palsy were similar to those in the group with Parkinson's disease but were more pronounced. Autonomic dysfunction may have to be considered a feature of progressive supranuclear palsy.
对11例进行性核上性麻痹患者、26例年龄、用药情况、疾病严重程度和病程相匹配的帕金森病患者以及19名年龄匹配的对照者进行了自主神经功能评估。两组患者的副交感神经（深呼吸和瓦尔萨尔瓦动作时的心率反应）和交感神经（站立时血压下降和持续握力时血压升高）测试结果均异常。进行性核上性麻痹患者组的异常情况与帕金森病患者组相似，但更为明显。自主神经功能障碍可能必须被视为进行性核上性麻痹的一个特征。
