Magalhães Cristina M R, Vasconcelos Patricia A C, Pereira Marne R, Alves Natália R M, Gandolfi Lenora, Pratesi Riccardo
Pediatric Rheumatology Unit, Brasilia General Hospital, Federal District Health Department, and Graduate Programs in Health Sciences, University of Brasília, SQN 212-Bloco F-Apto 605, CEP 70-864060, Asa Norte, Brasília, DF, Brazil.
Trop Doct. 2009 Apr;39(2):99-101. doi: 10.1258/td.2008.080124.
This is a prospective study of a cohort of 70 children with Kawasaki disease (KD) admitted from April 2002 to April 2007 to a tertiary hospital in Brasilia, Brazil. Of the 70 children, only 32 (45.7%) were referred during the acute phase of the disease and only 15 (21.4%) were referred with the correct diagnosis. Coronary aneurysms were detected in 13 (18.5%). A high suspicion index is essential in order to detect new cases as KD is probably underdiagnosed in Brazil and other developing countries, and an early diagnosis will dramatically decrease its life-threatening complications.
这是一项对2002年4月至2007年4月期间入住巴西巴西利亚一家三级医院的70名川崎病(KD)患儿的队列进行的前瞻性研究。在这70名患儿中,只有32名(45.7%)在疾病急性期被转诊,只有15名(21.4%)被正确诊断后转诊。检测到13例(18.5%)有冠状动脉瘤。由于在巴西和其他发展中国家川崎病可能诊断不足,因此高度怀疑指数对于发现新病例至关重要,而早期诊断将显著降低其危及生命的并发症。