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莫尔滕诺植入物治疗黑人患者难治性青光眼

Molteno implants as a treatment for refractory glaucoma in black patients.

作者信息

Freedman J, Rubin B

机构信息

Department of Ophthalmology, State University of New York, Brooklyn.

出版信息

Arch Ophthalmol. 1991 Oct;109(10):1417-20. doi: 10.1001/archopht.1991.01080100097051.

Abstract

Eighty-two black patients with refractory glaucoma were treated with a single-plate Molteno implant inserted in a single-stage procedure. A successful outcome (intraocular pressure less than or equal to 21 mm Hg with or without adjunctive medical therapy) was achieved in 72% of the patients with a mean follow-up of 30 months. Success was achieved in 23 (73%) of the 31 patients with open angle glaucoma, 20 (83%) of the 24 patients with either aphakic or pseudophakic glaucoma, 12 (67%) of the 18 patients with neovascular glaucoma, four (80%) of the five patients with uveitic glaucoma, and two (50%) of the four patients with congenital glaucoma. All but four patients required additional medical therapy. Visual acuities remained the same or improved in 21 (68%) of the 31 patients with open angle glaucoma, 11 (61%) of the 18 with neovascular glaucoma, 19 (79%) of the 24 patients with aphakic/pseudophakic glaucoma, three (75%) of the four patients with congenital glaucoma, and four (80%) of the five patients with uveitic glaucoma. Complications included hyphema (18%), "kissing" choroidal effusion (6%), blocked tube (8%), flat anterior chamber (12%), cataracts (5%), Tenon's cyst (encapsulated bleb) (17%), uveitis (7%), phthisis bulbi (5%), and erosion of the silicone tube (1%).

摘要

82例难治性青光眼黑人患者接受了单阶段手术植入单盘式莫尔顿引流物。平均随访30个月,72%的患者取得了成功结果(眼压小于或等于21 mmHg,无论是否辅助药物治疗)。开角型青光眼31例患者中有23例(73%)成功,无晶状体或人工晶状体性青光眼24例患者中有20例(83%)成功,新生血管性青光眼18例患者中有12例(67%)成功,葡萄膜炎性青光眼5例患者中有4例(80%)成功,先天性青光眼4例患者中有2例(50%)成功。除4例患者外,所有患者均需要额外的药物治疗。开角型青光眼31例患者中有21例(68%)视力保持不变或提高,新生血管性青光眼18例患者中有11例(61%)视力保持不变或提高,无晶状体/人工晶状体性青光眼24例患者中有19例(79%)视力保持不变或提高,先天性青光眼4例患者中有3例(75%)视力保持不变或提高,葡萄膜炎性青光眼5例患者中有4例(80%)视力保持不变或提高。并发症包括前房积血(18%)、“亲吻”性脉络膜渗漏(6%)、引流管堵塞(8%)、无前房(12%)、白内障(5%)、眼球筋膜囊肿(包裹性滤过泡)(17%)、葡萄膜炎(7%)、眼球痨(5%)和硅胶管侵蚀(1%)。

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