Patel Chirag N, Smith Jonathan T, Rankine James J, Scarsbrook Andrew F
Department of Nuclear Medicine, St James's University Hospital, Leeds, UK.
Clin Nucl Med. 2009 Apr;34(4):254-7. doi: 10.1097/RLU.0b013e31819a205c.
A 20-year-old woman underwent magnetic resonance imaging of the spine for back pain, which demonstrated a solitary lesion in the T2 vertebral body suspicious for a metastasis. Subsequent computed tomography and bone scintigraphy identified several further sites of bony involvement but no primary malignancy. The patient was referred for F-18 FDG PET/CT which demonstrated intense FDG activity in the sternoclavicular and sacroiliac joints, in addition to the known thoracic vertebral body involvement suggesting spondyloarthropathy rather than malignant disease. During the course of investigations, the patient developed palmoplantar pustulosis leading to a diagnosis of SAPHO syndrome.
一名20岁女性因背痛接受了脊柱磁共振成像检查，结果显示T2椎体有一个孤立性病变，怀疑是转移瘤。随后的计算机断层扫描和骨闪烁显像发现了更多骨受累部位，但未发现原发性恶性肿瘤。该患者被转诊进行F-18 FDG PET/CT检查，结果显示除了已知的胸椎椎体受累外，胸锁关节和骶髂关节也有强烈的FDG活性，提示为脊柱关节病而非恶性疾病。在检查过程中，患者出现掌跖脓疱病，最终诊断为SAPHO综合征。
